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Unveiling the Antimycobacterial Potential of Novel 4-Alkoxyquinolines: Insights into Selectivity, Mechanism of Action, and In Vivo Exposure.
da Silva FF, Paz JD, Rambo RS, Gonçalves GA, Muniz MN, de Matos Czeczot A, Perelló MA, Berger A, González LC, Duarte LS, da Silva AB, Ferreira CAS, de Oliveira SD, Moura S, Bizarro CV, Basso LA, Machado P. da Silva FF, et al. Among authors: perello ma. J Med Chem. 2024 Dec 26;67(24):21781-21794. doi: 10.1021/acs.jmedchem.4c01302. Epub 2024 Dec 4. J Med Chem. 2024. PMID: 39630172 Free PMC article.
The Concentration of Liver-Expressed Antimicrobial Peptide 2 in Human Milk and Infant Plasma Is Positively Associated with Adiposity and Body Weight in the First Year of Life.
Kruger AL, Malpeli A, Sala M, Casado C, Mendez I, Fotia L, López M, Tournier A, Castrogiovanni D, Heredia F, Llovera R, Schiöth HB, Perelló M, Andreoli MF. Kruger AL, et al. Among authors: perello m. J Nutr. 2024 Nov;154(11):3388-3399. doi: 10.1016/j.tjnut.2024.09.008. Epub 2024 Sep 12. J Nutr. 2024. PMID: 39277116
Crystal structure of dihydroneopterin aldolase from Mycobacterium tuberculosis associated with 8-mercaptoguanine, and development of novel S8-functionalized analogues as inhibitors: Synthesis, enzyme inhibition, in vitro toxicity and antitubercular activity.
Czeczot AM, Muniz MN, Perelló MA, Silva ÉED, Timmers LFSM, Berger A, Gonzalez LC, Arraché Gonçalves G, Moura S, Machado P, Bizarro CV, Basso LA. Czeczot AM, et al. Among authors: perello ma. J Enzyme Inhib Med Chem. 2024 Dec;39(1):2388207. doi: 10.1080/14756366.2024.2388207. Epub 2024 Aug 14. J Enzyme Inhib Med Chem. 2024. PMID: 39140692 Free PMC article.
Identification of antimycobacterial 8-hydroxyquinoline derivatives as in vitro enzymatic inhibitors of Mycobacterium tuberculosis enoyl-acyl carrier protein reductase.
Joaquim AR, Lopes MS, Fortes IS, de Bem Gentz C, de Matos Czeczot A, Perelló MA, Roth CD, Vainstein MH, Basso LA, Bizarro CV, Machado P, de Andrade SF. Joaquim AR, et al. Among authors: perello ma. Bioorg Chem. 2024 Oct;151:107705. doi: 10.1016/j.bioorg.2024.107705. Epub 2024 Aug 10. Bioorg Chem. 2024. PMID: 39137600
225 results