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IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas.
Sari G, Dhatchinamoorthy K, Orellano-Ariza L, Ferreira LM, Brehm MA, Rock K. Sari G, et al. Res Sq [Preprint]. 2024 Sep 2:rs.3.rs-4997954. doi: 10.21203/rs.3.rs-4997954/v1. Res Sq. 2024. Update in: J Exp Clin Cancer Res. 2024 Oct 2;43(1):276. doi: 10.1186/s13046-024-03187-5 PMID: 39281881 Free PMC article. Updated. Preprint.
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