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Page 1
Molecular glues that inhibit deubiquitylase activity and inflammatory signalling.
Chandler F, Reddy PAN, Bhutda S, Ross RL, Datta A, Walden M, Walker K, Di Donato S, Cassel JA, Prakesch MA, Aman A, Datti A, Campbell LJ, Foglizzo M, Bell L, Stein DN, Ault JR, Al-Awar RS, Calabrese AN, Sicheri F, Del Galdo F, Salvino JM, Greenberg RA, Zeqiraj E. Chandler F, et al. Among authors: al awar rs. bioRxiv [Preprint]. 2024 Nov 15:2024.09.07.611787. doi: 10.1101/2024.09.07.611787. bioRxiv. 2024. PMID: 39282282 Free PMC article. Preprint.
Lineage-defined leiomyosarcoma subtypes emerge years before diagnosis and determine patient survival.
Anderson ND, Babichev Y, Fuligni F, Comitani F, Layeghifard M, Venier RE, Dentro SC, Maheshwari A, Guram S, Wunker C, Thompson JD, Yuki KE, Hou H, Zatzman M, Light N, Bernardini MQ, Wunder JS, Andrulis IL, Ferguson P, Razak ARA, Swallow CJ, Dowling JJ, Al-Awar RS, Marcellus R, Rouzbahman M, Gerstung M, Durocher D, Alexandrov LB, Dickson BC, Gladdy RA, Shlien A. Anderson ND, et al. Among authors: al awar rs. Nat Commun. 2021 Jul 23;12(1):4496. doi: 10.1038/s41467-021-24677-6. Nat Commun. 2021. PMID: 34301934 Free PMC article.
Asymmetric synthesis of all the known phlegmarine alkaloids.
Wolfe BH, Libby AH, Al-Awar RS, Foti CJ, Comins DL. Wolfe BH, et al. Among authors: al awar rs. J Org Chem. 2010 Dec 17;75(24):8564-70. doi: 10.1021/jo1019688. Epub 2010 Nov 15. J Org Chem. 2010. PMID: 21077636 Free PMC article.
Cryptophycins-309, 249 and other cryptophycin analogs: preclinical efficacy studies with mouse and human tumors.
Liang J, Moore RE, Moher ED, Munroe JE, Al-awar RS, Hay DA, Varie DL, Zhang TY, Aikins JA, Martinelli MJ, Shih C, Ray JE, Gibson LL, Vasudevan V, Polin L, White K, Kushner J, Simpson C, Pugh S, Corbett TH. Liang J, et al. Among authors: al awar rs. Invest New Drugs. 2005 Jun;23(3):213-24. doi: 10.1007/s10637-005-6729-9. Invest New Drugs. 2005. PMID: 15868377
15 results