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Test-retest precision and longitudinal cartilage thickness loss in the IMI-APPROACH cohort.
Wirth W, Maschek S, Marijnissen ACA, Lalande A, Blanco FJ, Berenbaum F, van de Stadt LA, Kloppenburg M, Haugen IK, Ladel CH, Bacardit J, Wisser A, Eckstein F, Roemer FW, Lafeber FPJG, Weinans HH, Jansen M. Wirth W, et al. Among authors: ladel ch. Osteoarthritis Cartilage. 2023 Feb;31(2):238-248. doi: 10.1016/j.joca.2022.10.015. Epub 2022 Nov 3. Osteoarthritis Cartilage. 2023. PMID: 36336198 Free article. Clinical Trial.
Reflections from the OARSI 2022 clinical trials symposium: The pain of OA-Deconstruction of pain and patient-reported outcome measures for the benefit of patients and clinical trial design.
Karsdal MA, Tambiah J, Felson D, Ladel C, Nikolov NP, Hodgins D, Bihlet AR, Neogi T, Baatenburg de Jong C, Bay-Jensen AC, Baron R, Laslop A, Mobasheri A, Kraus VB. Karsdal MA, et al. Among authors: ladel c. Osteoarthritis Cartilage. 2023 Oct;31(10):1293-1302. doi: 10.1016/j.joca.2023.06.006. Epub 2023 Jun 26. Osteoarthritis Cartilage. 2023. PMID: 37380011 Free PMC article. Review.
Safety, Tolerability, and Pharmacodynamics of the ADAMTS-5 Nanobody M6495: Two Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Studies in Healthy Subjects and Patients With Osteoarthritis.
Bihlet AR, Balchen T, Goteti K, Sonne J, Ladel C, Karsdal MA, Ona V, Moreau F, Waterhouse R, Bay-Jensen AC, Guehring H. Bihlet AR, et al. Among authors: ladel c. ACR Open Rheumatol. 2024 Apr;6(4):205-213. doi: 10.1002/acr2.11610. Epub 2024 Feb 4. ACR Open Rheumatol. 2024. PMID: 38311369 Free PMC article.
Is detection of disease-modifying osteoarthritis drug treatment more effective when performing cartilage morphometry without blinding to MR image acquisition order?
Eckstein F, Wisser A, Maschek S, Wirth W, Ladel C, Bihlet AR, Knight C, Somberg K, Zhao L. Eckstein F, et al. Among authors: ladel c. Osteoarthritis Cartilage. 2024 Oct;32(10):1346-1351. doi: 10.1016/j.joca.2024.05.012. Epub 2024 Jun 4. Osteoarthritis Cartilage. 2024. PMID: 38844160 Free article. Clinical Trial.
Longitudinal stability of molecular endotypes of knee osteoarthritis patients.
Hannani MT, Thudium CS, Gellhorn AC, Larkin J, Karsdal MA, Lisowska-Petersen Z, Frederiksen P, Bager CL, Ladel C, Struglics A, Uebelhoer M, Henrotin Y, Bihlet AR, Blanco FJ, Haugen IK, Kloppenburg M, Berenbaum F, Mobasheri A, Bacardit J, Bay-Jensen AC. Hannani MT, et al. Among authors: ladel c. Osteoarthritis Cartilage. 2025 Jan;33(1):166-175. doi: 10.1016/j.joca.2024.11.002. Epub 2024 Nov 8. Osteoarthritis Cartilage. 2025. PMID: 39522936 Free article.
Development and validation of a machine learning-supported strategy of patient selection for osteoarthritis clinical trials: the IMI-APPROACH study.
Widera P, Welsing PMJ, Danso SO, Peelen S, Kloppenburg M, Loef M, Marijnissen AC, van Helvoort EM, Blanco FJ, Magalhães J, Berenbaum F, Haugen IK, Bay-Jensen AC, Mobasheri A, Ladel C, Loughlin J, Lafeber FPJG, Lalande A, Larkin J, Weinans H, Bacardit J. Widera P, et al. Among authors: ladel c. Osteoarthr Cartil Open. 2023 Aug 18;5(4):100406. doi: 10.1016/j.ocarto.2023.100406. eCollection 2023 Dec. Osteoarthr Cartil Open. 2023. PMID: 37649530 Free PMC article.
Reflections from the 2021 OARSI clinical trial symposium: Considerations for understanding biomarker assessments in osteoarthritis drug development - Should future studies focus on disease activity, rather than status?
Karsdal MA, Tambiah J, Hochberg MC, Ladel C, Bay-Jensen AC, Arendt-Nielsen L, Mobasheri A, Kraus VB. Karsdal MA, et al. Among authors: ladel c. Osteoarthr Cartil Open. 2022 Apr 28;4(3):100262. doi: 10.1016/j.ocarto.2022.100262. eCollection 2022 Sep. Osteoarthr Cartil Open. 2022. PMID: 36474940 Free PMC article.
90 results