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Page 1
HLA A*24:02-restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes.
Dolton G, Bulek A, Wall A, Thomas H, Hopkins JR, Rius C, Galloway SA, Whalley T, Tan LR, Morin T, Omidvar N, Fuller A, Topley K, Hasan MS, Jain S, D'Souza N, Hodges-Hoyland T; TIRID Consortium; Spiller OB, Kronenberg-Versteeg D, Szomolay B, van den Berg HA, Jones LC, Peakman M, Cole DK, Rizkallah PJ, Sewell AK. Dolton G, et al. Among authors: bulek a. J Clin Invest. 2024 Sep 17;134(18):e164535. doi: 10.1172/JCI164535. J Clin Invest. 2024. PMID: 39286976 Free PMC article.
Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies.
Ferrari M, Righi M, Baldan V, Wawrzyniecka P, Bulek A, Kinna A, Ma B, Bughda R, Akbar Z, Srivastava S, Gannon I, Robson M, Sillibourne J, Jha R, El-Kholy M, Amin OM, Kokalaki E, Banani MA, Hussain R, Day W, Lim WC, Ghongane P, Hopkins JR, Jungherz D, Herling M, Welin M, Surade S, Dyson M, McCafferty J, Logan D, Cordoba S, Thomas S, Sewell A, Maciocia P, Onuoha S, Pule M. Ferrari M, et al. Among authors: bulek a. Nat Commun. 2024 Feb 21;15(1):1583. doi: 10.1038/s41467-024-45854-3. Nat Commun. 2024. PMID: 38383515 Free PMC article.
Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein-Protein Interaction.
Jha R, Kinna A, Hotblack A, Bughda R, Bulek A, Gannon I, Ilca T, Allen C, Lamb K, Dolor A, Scott I, Parekh F, Sillibourne J, Cordoba S, Onuoha S, Thomas S, Ferrari M, Pule M. Jha R, et al. Among authors: bulek a. ACS Chem Biol. 2024 Feb 16;19(2):308-324. doi: 10.1021/acschembio.3c00521. Epub 2024 Jan 20. ACS Chem Biol. 2024. PMID: 38243811 Free PMC article.
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Kokalaki E, Ma B, Ferrari M, Grothier T, Hazelton W, Manzoor S, Costu E, Taylor J, Bulek A, Srivastava S, Gannon I, Jha R, Gealy R, Stanczuk L, Rizou T, Robson M, El-Kholy M, Baldan V, Righi M, Sillibourne J, Thomas S, Onuoha S, Cordoba S, Pule M. Kokalaki E, et al. Among authors: bulek a. Mol Ther. 2024 Feb 7;32(2):556-558. doi: 10.1016/j.ymthe.2023.12.006. Epub 2023 Dec 15. Mol Ther. 2024. PMID: 38103549 Free article. No abstract available.
Exploration of T cell immune responses by expression of a dominant-negative SHP1 and SHP2.
Taylor J, Bulek A, Gannon I, Robson M, Kokalaki E, Grothier T, McKenzie C, El-Kholy M, Stavrou M, Traynor-White C, Lim WC, Panagiotou P, Srivastava S, Baldan V, Sillibourne J, Ferrari M, Pule M, Thomas S. Taylor J, et al. Among authors: bulek a. Front Immunol. 2023 Jun 2;14:1119350. doi: 10.3389/fimmu.2023.1119350. eCollection 2023. Front Immunol. 2023. PMID: 37334382 Free PMC article.
Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR.
Kokalaki E, Ma B, Ferrari M, Grothier T, Hazelton W, Manzoor S, Costu E, Taylor J, Bulek A, Srivastava S, Gannon I, Jha R, Gealy R, Stanczuk L, Rizou T, Robson M, El-Kholy M, Baldan V, Righi M, Sillibourne J, Thomas S, Onuoha S, Cordoba S, Pule M. Kokalaki E, et al. Among authors: bulek a. Mol Ther. 2023 Jul 5;31(7):2089-2104. doi: 10.1016/j.ymthe.2023.03.020. Epub 2023 Mar 21. Mol Ther. 2023. PMID: 36945773 Free PMC article.
TCR-induced alteration of primary MHC peptide anchor residue.
Madura F, Rizkallah PJ, Legut M, Holland CJ, Fuller A, Bulek A, Schauenburg AJ, Trimby A, Hopkins JR, Wells SA, Godkin A, Miles JJ, Sami M, Li Y, Liddy N, Jakobsen BK, Loveridge EJ, Cole DK, Sewell AK. Madura F, et al. Among authors: bulek a. Eur J Immunol. 2019 Jul;49(7):1052-1066. doi: 10.1002/eji.201948085. Epub 2019 May 27. Eur J Immunol. 2019. PMID: 31091334 Free PMC article.
In Silico and Structural Analyses Demonstrate That Intrinsic Protein Motions Guide T Cell Receptor Complementarity Determining Region Loop Flexibility.
Holland CJ, MacLachlan BJ, Bianchi V, Hesketh SJ, Morgan R, Vickery O, Bulek AM, Fuller A, Godkin A, Sewell AK, Rizkallah PJ, Wells S, Cole DK. Holland CJ, et al. Among authors: bulek am. Front Immunol. 2018 Apr 11;9:674. doi: 10.3389/fimmu.2018.00674. eCollection 2018. Front Immunol. 2018. PMID: 29696015 Free PMC article.
Dual Molecular Mechanisms Govern Escape at Immunodominant HLA A2-Restricted HIV Epitope.
Cole DK, Fuller A, Dolton G, Zervoudi E, Legut M, Miles K, Blanchfield L, Madura F, Holland CJ, Bulek AM, Bridgeman JS, Miles JJ, Schauenburg AJA, Beck K, Evavold BD, Rizkallah PJ, Sewell AK. Cole DK, et al. Among authors: bulek am. Front Immunol. 2017 Nov 10;8:1503. doi: 10.3389/fimmu.2017.01503. eCollection 2017. Front Immunol. 2017. PMID: 29209312 Free PMC article.
23 results