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Targeting senescence.
Serrano M, Barzilai N. Serrano M, et al. Nat Med. 2018 Aug;24(8):1092-1094. doi: 10.1038/s41591-018-0141-4. Nat Med. 2018. PMID: 30082861 No abstract available.
Cellular Senescence in Lung Fibrosis.
Hernandez-Gonzalez F, Faner R, Rojas M, Agustí A, Serrano M, Sellarés J. Hernandez-Gonzalez F, et al. Among authors: serrano m. Int J Mol Sci. 2021 Jun 29;22(13):7012. doi: 10.3390/ijms22137012. Int J Mol Sci. 2021. PMID: 34209809 Free PMC article. Review.
The lysosomal proteome of senescent cells contributes to the senescence secretome.
Rovira M, Sereda R, Pladevall-Morera D, Ramponi V, Marin I, Maus M, Madrigal-Matute J, Díaz A, García F, Muñoz J, Cuervo AM, Serrano M. Rovira M, et al. Among authors: serrano m. Aging Cell. 2022 Oct;21(10):e13707. doi: 10.1111/acel.13707. Epub 2022 Sep 10. Aging Cell. 2022. PMID: 36087066 Free PMC article.
Cellular Senescence Is Immunogenic and Promotes Antitumor Immunity.
Marin I, Boix O, Garcia-Garijo A, Sirois I, Caballe A, Zarzuela E, Ruano I, Attolini CS, Prats N, López-Domínguez JA, Kovatcheva M, Garralda E, Muñoz J, Caron E, Abad M, Gros A, Pietrocola F, Serrano M. Marin I, et al. Among authors: serrano m. Cancer Discov. 2023 Feb 6;13(2):410-431. doi: 10.1158/2159-8290.CD-22-0523. Cancer Discov. 2023. PMID: 36302218 Free PMC article.
Hallmarks of aging: An expanding universe.
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. López-Otín C, et al. Among authors: serrano m. Cell. 2023 Jan 19;186(2):243-278. doi: 10.1016/j.cell.2022.11.001. Epub 2023 Jan 3. Cell. 2023. PMID: 36599349 Free article. Review.
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype.
Maus M, López-Polo V, Mateo L, Lafarga M, Aguilera M, De Lama E, Meyer K, Sola A, Lopez-Martinez C, López-Alonso I, Guasch-Piqueras M, Hernandez-Gonzalez F, Chaib S, Rovira M, Sanchez M, Faner R, Agusti A, Diéguez-Hurtado R, Ortega S, Manonelles A, Engelhardt S, Monteiro F, Stephan-Otto Attolini C, Prats N, Albaiceta G, Cruzado JM, Serrano M. Maus M, et al. Among authors: serrano m. Nat Metab. 2023 Dec;5(12):2111-2130. doi: 10.1038/s42255-023-00928-2. Epub 2023 Dec 14. Nat Metab. 2023. PMID: 38097808 Free PMC article.
The efficacy of chemotherapy is limited by intratumoral senescent cells expressing PD-L2.
Chaib S, López-Domínguez JA, Lalinde-Gutiérrez M, Prats N, Marin I, Boix O, García-Garijo A, Meyer K, Muñoz MI, Aguilera M, Mateo L, Stephan-Otto Attolini C, Llanos S, Pérez-Ramos S, Escorihuela M, Al-Shahrour F, Cash TP, Tchkonia T, Kirkland JL, Abad M, Gros A, Arribas J, Serrano M. Chaib S, et al. Among authors: serrano m. Nat Cancer. 2024 Mar;5(3):448-462. doi: 10.1038/s43018-023-00712-x. Epub 2024 Jan 24. Nat Cancer. 2024. PMID: 38267628 Free PMC article.
2,022 results