Makumire S - Search Results

1

Structure of Plasmodium vivaxN-myristoyltransferase with inhibitor IMP-1088: exploring an NMT inhibitor for antimalarial therapy.

Mendez A, Bolling C, Taylor S, Makumire S, Staker B, Reers A, Hammerson B, Mayclin SJ, Abendroth J, Lorimer DD, Edwards TE, Tate EW, Subramanian S, Bell AS, Myler PJ, Asojo OA, Chakafana G. Mendez A, et al. Among authors: makumire s. Acta Crystallogr F Struct Biol Commun. 2025 Jan 1;81(Pt 1):1-10. doi: 10.1107/S2053230X24011348. Epub 2025 Jan 1. Acta Crystallogr F Struct Biol Commun. 2025. PMID: 39655507 Free PMC article.

2

Ternary structure of Plasmodium vivaxN-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173.

Bolling C, Mendez A, Taylor S, Makumire S, Reers A, Zigweid R, Subramanian S, Dranow DM, Staker B, Edwards TE, Tate EW, Bell AS, Myler PJ, Asojo OA, Chakafana G. Bolling C, et al. Among authors: makumire s. Acta Crystallogr F Struct Biol Commun. 2024 Oct 1;80(Pt 10):269-277. doi: 10.1107/S2053230X24008604. Epub 2024 Sep 18. Acta Crystallogr F Struct Biol Commun. 2024. PMID: 39291304 Free PMC article.

3

Editorial: Molecular chaperones and human disease.

Chakafana G, Makumire S, Makhoba XH. Chakafana G, et al. Among authors: makumire s. Front Mol Biosci. 2022 Nov 17;9:1068238. doi: 10.3389/fmolb.2022.1068238. eCollection 2022. Front Mol Biosci. 2022. PMID: 36465555 Free PMC article. No abstract available.

4

Inhibition of Plasmodium falciparum Hsp70-Hop partnership by 2-phenylthynesulfonamide.

Muthelo T, Mulaudzi V, Netshishivhe M, Dongola TH, Kok M, Makumire S, de Villiers M, Burger A, Zininga T, Shonhai A. Muthelo T, et al. Among authors: makumire s. Front Mol Biosci. 2022 Sep 13;9:947203. doi: 10.3389/fmolb.2022.947203. eCollection 2022. Front Mol Biosci. 2022. PMID: 36177352 Free PMC article.

5

The structures of the C146A variant of the amidase from Pyrococcus horikoshii bound to glutaramide and acetamide suggest the basis of amide recognition.

Makumire S, Su S, Weber BW, Woodward JD, Wangari Kimani S, Hunter R, Sewell BT. Makumire S, et al. J Struct Biol. 2022 Jun;214(2):107859. doi: 10.1016/j.jsb.2022.107859. Epub 2022 Apr 16. J Struct Biol. 2022. PMID: 35439644

6

The capture of host cell's resources: The role of heat shock proteins and polyamines in SARS-COV-2 (COVID-19) pathway to viral infection.

Makhoba XH, Makumire S. Makhoba XH, et al. Among authors: makumire s. Biomol Concepts. 2022 Apr 19;13(1):220-229. doi: 10.1515/bmc-2022-0008. Biomol Concepts. 2022. PMID: 35437978 Free article. Review.

7

Bioprospecting for Novel Heat Shock Protein Modulators: The New Frontier for Antimalarial Drug Discovery?

Anokwuru C, Makumire S, Shonhai A. Anokwuru C, et al. Among authors: makumire s. Adv Exp Med Biol. 2021;1340:187-203. doi: 10.1007/978-3-030-78397-6_8. Adv Exp Med Biol. 2021. PMID: 34569026

8

Mutation of GGMP Repeat Segments of Plasmodium falciparum Hsp70-1 Compromises Chaperone Function and Hop Co-Chaperone Binding.

Makumire S, Dongola TH, Chakafana G, Tshikonwane L, Chauke CT, Maharaj T, Zininga T, Shonhai A. Makumire S, et al. Int J Mol Sci. 2021 Feb 23;22(4):2226. doi: 10.3390/ijms22042226. Int J Mol Sci. 2021. PMID: 33672387 Free PMC article.

9

Biophysical analysis of Plasmodium falciparum Hsp70-Hsp90 organising protein (PfHop) reveals a monomer that is characterised by folded segments connected by flexible linkers.

Makumire S, Zininga T, Vahokoski J, Kursula I, Shonhai A. Makumire S, et al. PLoS One. 2020 Apr 28;15(4):e0226657. doi: 10.1371/journal.pone.0226657. eCollection 2020. PLoS One. 2020. PMID: 32343703 Free PMC article.

10

Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif.

Mabate B, Zininga T, Ramatsui L, Makumire S, Achilonu I, Dirr HW, Shonhai A. Mabate B, et al. Among authors: makumire s. Proteins. 2018 Nov;86(11):1189-1201. doi: 10.1002/prot.25600. Epub 2018 Sep 29. Proteins. 2018. PMID: 30183110 Free PMC article.

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