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BWC0977, a broad-spectrum antibacterial clinical candidate to treat multidrug resistant infections.
Hameed P S, Kotakonda H, Sharma S, Nandishaiah R, Katagihallimath N, Rao R, Sadler C, Slater I, Morton M, Chandrasekaran A, Griffen E, Pillai D, Reddy S, Bharatham N, Venkatesan S, Jonnalagadda V, Jayaraman R, Nanjundappa M, Sharma M, Raveendran S, Rajagopal S, Tumma H, Watters A, Becker H, Lindley J, Flamm R, Huband M, Sahm D, Hackel M, Mathur T, Kolamunnage-Dona R, Unsworth J, Mcentee L, Farrington N, Manickam D, Chandrashekara N, Jayachandiran S, Reddy H, Shanker S, Richard V, Thomas T, Nagaraj S, Datta S, Sambandamurthy V, Ramachandran V, Clay R, Tomayko J, Das S, V B. Hameed P S, et al. Among authors: lindley j. Nat Commun. 2024 Sep 18;15(1):8202. doi: 10.1038/s41467-024-52557-2. Nat Commun. 2024. PMID: 39294149 Free PMC article. Clinical Trial.
In Vitro Activity of KBP-7072, a Novel Third-Generation Tetracycline, against 531 Recent Geographically Diverse and Molecularly Characterized Acinetobacter baumannii Species Complex Isolates.
Huband MD, Mendes RE, Pfaller MA, Lindley JM, Strand GJ, Benn VJ, Zhang J, Li L, Zhang M, Tan X, Liu Q, Flamm RK. Huband MD, et al. Among authors: lindley jm. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02375-19. doi: 10.1128/AAC.02375-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32071042 Free PMC article.
Evaluation of the Bactericidal Activity of Fosfomycin in Combination with Selected Antimicrobial Comparison Agents Tested against Gram-Negative Bacterial Strains by Using Time-Kill Curves.
Flamm RK, Rhomberg PR, Lindley JM, Sweeney K, Ellis-Grosse EJ, Shortridge D. Flamm RK, et al. Among authors: lindley jm. Antimicrob Agents Chemother. 2019 Apr 25;63(5):e02549-18. doi: 10.1128/AAC.02549-18. Print 2019 May. Antimicrob Agents Chemother. 2019. PMID: 30858207 Free PMC article.
In vitro activity of KHP-3757 (a novel LpxC inhibitor) and comparator agents against recent and molecularly characterized Pseudomonas aeruginosa isolates from a global surveillance program (2017-2018).
Huband MD, Lindley JM, Mendes RE, Fedler KA, Benn VJ, Zhang J, Zhong G, Li L, Zhang M, Tan X, Flamm RK. Huband MD, et al. Among authors: lindley jm. Diagn Microbiol Infect Dis. 2020 Dec;98(4):115191. doi: 10.1016/j.diagmicrobio.2020.115191. Epub 2020 Aug 24. Diagn Microbiol Infect Dis. 2020. PMID: 32950854
In vitro activity of a novel aminomethylcycline antibacterial (KBP-7072), a third-generation tetracycline, against clinical isolates with molecularly characterized tetracycline resistance mechanisms.
Pfaller MA, Li L, Liu Q, Zhang J, Huband MD, Lindley JM, Mendes RE. Pfaller MA, et al. Among authors: lindley jm. JAC Antimicrob Resist. 2021 Dec 14;3(4):dlab177. doi: 10.1093/jacamr/dlab177. eCollection 2021 Dec. JAC Antimicrob Resist. 2021. PMID: 34917942 Free PMC article.
In Vitro Activity of the Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 in Combination with Multiple Beta-Lactam Antibiotics against Pseudomonas aeruginosa.
Lomovskaya O, Rubio-Aparicio D, Nelson K, Sun D, Tsivkovski R, Castanheira M, Lindley J, Loutit J, Dudley M. Lomovskaya O, et al. Among authors: lindley j. Antimicrob Agents Chemother. 2021 May 18;65(6):e00210-21. doi: 10.1128/AAC.00210-21. Print 2021 May 18. Antimicrob Agents Chemother. 2021. PMID: 33782010 Free PMC article.
In vitro potency of xeruborbactam in combination with multiple β-lactam antibiotics in comparison with other β-lactam/β-lactamase inhibitor (BLI) combinations against carbapenem-resistant and extended-spectrum β-lactamase-producing Enterobacterales.
Lomovskaya O, Castanheira M, Lindley J, Rubio-Aparicio D, Nelson K, Tsivkovski R, Sun D, Totrov M, Loutit J, Dudley M. Lomovskaya O, et al. Among authors: lindley j. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0044023. doi: 10.1128/aac.00440-23. Epub 2023 Oct 6. Antimicrob Agents Chemother. 2023. PMID: 37800963 Free PMC article.
91 results