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Topical adjunctive treatment with flagellin augments pulmonary neutrophil responses and reduces bacterial dissemination in multidrug-resistant K. pneumoniae infection.
van Linge CCA, Kullberg RFJ, Chouchane O, Roelofs JJTH, Goessens WHF, van 't Veer C, Sirard JC, de Vos AF, van der Poll T. van Linge CCA, et al. Among authors: sirard jc. Front Immunol. 2024 Sep 4;15:1450486. doi: 10.3389/fimmu.2024.1450486. eCollection 2024. Front Immunol. 2024. PMID: 39295863 Free PMC article.
A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection.
Liu X, Van Maele L, Matarazzo L, Soulard D, Alves Duarte da Silva V, de Bakker V, Dénéréaz J, Bock FP, Taschner M, Ou J, Gruber S, Nizet V, Sirard JC, Veening JW. Liu X, et al. Among authors: sirard jc. Cell Host Microbe. 2024 Mar 13;32(3):304-314.e8. doi: 10.1016/j.chom.2024.02.002. Epub 2024 Feb 27. Cell Host Microbe. 2024. PMID: 38417443 Free article.
Competence remodels the pneumococcal cell wall exposing key surface virulence factors that mediate increased host adherence.
Minhas V, Domenech A, Synefiaridou D, Straume D, Brendel M, Cebrero G, Liu X, Costa C, Baldry M, Sirard JC, Perez C, Gisch N, Hammerschmidt S, Håvarstein LS, Veening JW. Minhas V, et al. Among authors: sirard jc. PLoS Biol. 2023 Jan 30;21(1):e3001990. doi: 10.1371/journal.pbio.3001990. eCollection 2023 Jan. PLoS Biol. 2023. PMID: 36716340 Free PMC article.
108 results