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CCR2/CCR5 inhibitor permits the radiation-induced effector T cell infiltration in pancreatic adenocarcinoma.
Wang J, Saung MT, Li K, Fu J, Fujiwara K, Niu N, Muth S, Wang J, Xu Y, Rozich N, Zlomke H, Chen S, Espinoza B, Henderson M, Funes V, Herbst B, Ding D, Twyman-Saint Victor C, Zhao Q, Narang A, He J, Zheng L. Wang J, et al. Among authors: fu j. J Exp Med. 2022 May 2;219(5):e20211631. doi: 10.1084/jem.20211631. Epub 2022 Apr 11. J Exp Med. 2022. PMID: 35404390 Free PMC article.
CLDN18.2 BiTE Engages Effector and Regulatory T Cells for Antitumor Immune Response in Preclinical Models of Pancreatic Cancer.
Xu Y, Fu J, Henderson M, Lee F, Jurcak N, Henn A, Wahl J, Shao Y, Wang J, Lyman M, Funes V, Espinoza B, Zhang R, Washington I, Chen SY, Zlomke H, Wang J, Niu N, Li P, Meng F, Burns W, Friedrich M, Stienen S, Bailis JM, Zheng L. Xu Y, et al. Among authors: fu j. Gastroenterology. 2023 Nov;165(5):1219-1232. doi: 10.1053/j.gastro.2023.06.037. Epub 2023 Jul 26. Gastroenterology. 2023. PMID: 37507075 Free PMC article.
Mesothelin CAR T Cells Secreting Anti-FAP/Anti-CD3 Molecules Efficiently Target Pancreatic Adenocarcinoma and its Stroma.
Wehrli M, Guinn S, Birocchi F, Kuo A, Sun Y, Larson RC, Almazan AJ, Scarfò I, Bouffard AA, Bailey SR, Anekal PV, Montero Llopis P, Nieman LT, Song Y, Xu KH, Berger TR, Kann MC, Leick MB, Silva H, Salas-Benito D, Kienka T, Grauwet K, Armstrong TD, Zhang R, Zhu Q, Fu J, Schmidts A, Korell F, Jan M, Choi BD, Liss AS, Boland GM, Ting DT, Burkhart RA, Jenkins RW, Zheng L, Jaffee EM, Zimmerman JW, Maus MV. Wehrli M, et al. Among authors: fu j. Clin Cancer Res. 2024 May 1;30(9):1859-1877. doi: 10.1158/1078-0432.CCR-23-3841. Clin Cancer Res. 2024. PMID: 38393682 Free PMC article.
Overcome the challenge for intratumoral injection of STING agonist for pancreatic cancer by systemic administration.
Li K, Wang J, Zhang R, Zhou J, Espinoza B, Niu N, Wang J, Jurcak N, Rozich N, Osipov A, Henderson M, Funes V, Lyman M, Blair AB, Herbst B, He M, Yuan J, Trafton D, Yuan C, Wichroski M, Liu X, Fu J, Zheng L. Li K, et al. Among authors: fu j. J Hematol Oncol. 2024 Aug 7;17(1):62. doi: 10.1186/s13045-024-01576-z. J Hematol Oncol. 2024. PMID: 39113096 Free PMC article.
Semaphorin 3D promotes pancreatic ductal adenocarcinoma progression and metastasis through macrophage reprogramming.
Thielman NRJ, Funes V, Davuluri S, Ibanez HE, Sun WC, Fu J, Li K, Muth S, Pan X, Fujiwara K, Dwayne L Thomas Ii, Henderson M, Teh SS, Zhu Q, Thompson E, Jaffee EM, Kolodkin A, Meng F, Zheng L. Thielman NRJ, et al. Among authors: fu j. Sci Adv. 2024 Oct 18;10(42):eadp0684. doi: 10.1126/sciadv.adp0684. Epub 2024 Oct 16. Sci Adv. 2024. PMID: 39413197 Free article.
Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy.
Zheng Y, Lebid A, Chung L, Fu J, Wang X, Otrocol A, Zarif JC, Yu H, Llosa NJ, Pardoll DM. Zheng Y, et al. Among authors: fu j. Oncoimmunology. 2024 Jan 8;13(1):2297503. doi: 10.1080/2162402X.2023.2297503. eCollection 2024. Oncoimmunology. 2024. PMID: 38235319 Free PMC article.
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