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Page 1
Immune profiling-based targeting of pathogenic T cells with ustekinumab in ANCA-associated glomerulonephritis.
Engesser J, Khatri R, Schaub DP, Zhao Y, Paust HJ, Sultana Z, Asada N, Riedel JH, Sivayoganathan V, Peters A, Kaffke A, Jauch-Speer SL, Goldbeck-Strieder T, Puelles VG, Wenzel UO, Steinmetz OM, Hoxha E, Turner JE, Mittrücker HW, Wiech T, Huber TB, Bonn S, Krebs CF, Panzer U. Engesser J, et al. Among authors: turner je. Nat Commun. 2024 Sep 19;15(1):8220. doi: 10.1038/s41467-024-52525-w. Nat Commun. 2024. PMID: 39300109 Free PMC article.
Renal IL-17 expression in human ANCA-associated glomerulonephritis.
Velden J, Paust HJ, Hoxha E, Turner JE, Steinmetz OM, Wolf G, Jabs WJ, Özcan F, Beige J, Heering PJ, Schröder S, Kneißler U, Disteldorf E, Mittrücker HW, Stahl RA, Helmchen U, Panzer U. Velden J, et al. Among authors: turner je. Am J Physiol Renal Physiol. 2012 Jun 15;302(12):F1663-73. doi: 10.1152/ajprenal.00683.2011. Epub 2012 Mar 21. Am J Physiol Renal Physiol. 2012. PMID: 22442208 Free article.
Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease.
Krebs CF, Reimers D, Zhao Y, Paust HJ, Bartsch P, Nuñez S, Rosemblatt MV, Hellmig M, Kilian C, Borchers A, Enk LUB, Zinke M, Becker M, Schmid J, Klinge S, Wong MN, Puelles VG, Schmidt C, Bertram T, Stumpf N, Hoxha E, Meyer-Schwesinger C, Lindenmeyer MT, Cohen CD, Rink M, Kurts C, Franzenburg S, Koch-Nolte F, Turner JE, Riedel JH, Huber S, Gagliani N, Huber TB, Wiech T, Rohde H, Bono MR, Bonn S, Panzer U, Mittrücker HW. Krebs CF, et al. Among authors: turner je. Sci Immunol. 2020 Aug 7;5(50):eaba4163. doi: 10.1126/sciimmunol.aba4163. Sci Immunol. 2020. PMID: 32769171
Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury.
Riedel JH, Robben L, Paust HJ, Zhao Y, Asada N, Song N, Peters A, Kaffke A, Borchers A, Tiegs G, Seifert L, Tomas NM, Hoxha E, Wenzel UO, Huber TB, Wiech T, Turner JE, Krebs CF, Panzer U. Riedel JH, et al. Among authors: turner je. JCI Insight. 2023 Jan 10;8(1):e160251. doi: 10.1172/jci.insight.160251. JCI Insight. 2023. PMID: 36355429 Free PMC article.
CD4+ T cells produce GM-CSF and drive immune-mediated glomerular disease by licensing monocyte-derived cells to produce MMP12.
Paust HJ, Song N, De Feo D, Asada N, Tuzlak S, Zhao Y, Riedel JH, Hellmig M, Sivayoganathan A, Peters A, Kaffke A, Borchers A, Wenzel UO, Steinmetz OM, Tiegs G, Meister E, Mack M, Kurts C, von Vietinghoff S, Lindenmeyer MT, Hoxha E, Stahl RAK, Huber TB, Bonn S, Meyer-Schwesinger C, Wiech T, Turner JE, Becher B, Krebs CF, Panzer U. Paust HJ, et al. Among authors: turner je. Sci Transl Med. 2023 Mar 15;15(687):eadd6137. doi: 10.1126/scitranslmed.add6137. Epub 2023 Mar 15. Sci Transl Med. 2023. PMID: 36921033
Mucosal-associated invariant T cells contribute to suppression of inflammatory myeloid cells in immune-mediated kidney disease.
Gnirck AC, Philipp MS, Waterhölter A, Wunderlich M, Shaikh N, Adamiak V, Henneken L, Kautz T, Xiong T, Klaus D, Tomczyk P, Al-Bahra MM, Menche D, Walkenhorst M, Lantz O, Willing A, Friese MA, Huber TB, Krebs CF, Panzer U, Kurts C, Turner JE. Gnirck AC, et al. Among authors: turner je. Nat Commun. 2023 Nov 15;14(1):7372. doi: 10.1038/s41467-023-43269-0. Nat Commun. 2023. PMID: 37968302 Free PMC article.
The IL-23/Th17 axis contributes to renal injury in experimental glomerulonephritis.
Paust HJ, Turner JE, Steinmetz OM, Peters A, Heymann F, Hölscher C, Wolf G, Kurts C, Mittrücker HW, Stahl RA, Panzer U. Paust HJ, et al. Among authors: turner je. J Am Soc Nephrol. 2009 May;20(5):969-79. doi: 10.1681/ASN.2008050556. Epub 2009 Apr 1. J Am Soc Nephrol. 2009. PMID: 19339380 Free PMC article.
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.
Turner JE, Paust HJ, Steinmetz OM, Peters A, Riedel JH, Erhardt A, Wegscheid C, Velden J, Fehr S, Mittrücker HW, Tiegs G, Stahl RA, Panzer U. Turner JE, et al. J Am Soc Nephrol. 2010 Jun;21(6):974-85. doi: 10.1681/ASN.2009070741. Epub 2010 Mar 18. J Am Soc Nephrol. 2010. PMID: 20299360 Free PMC article.
464 results