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A B7-H3-targeted CD28 bispecific antibody enhances the activity of anti-PD1 and CD3 T-cell engager immunotherapies.
Moore GL, Zeng VG, Diaz JE, Bonzon C, Avery KN, Rashid R, Qi J, Nam DH, Jacinto J, Dragovich MA, Kim YK, Balcazar KP, Bakhit CG, Eivazi A, Nguyen H, Muchhal US, Szymkowski DE, Desjarlais JR, Hedvat M. Moore GL, et al. Among authors: eivazi a. Mol Cancer Ther. 2024 Sep 20. doi: 10.1158/1535-7163.MCT-24-0327. Online ahead of print. Mol Cancer Ther. 2024. PMID: 39301613
Inactivation of TNF signaling by rationally designed dominant-negative TNF variants.
Steed PM, Tansey MG, Zalevsky J, Zhukovsky EA, Desjarlais JR, Szymkowski DE, Abbott C, Carmichael D, Chan C, Cherry L, Cheung P, Chirino AJ, Chung HH, Doberstein SK, Eivazi A, Filikov AV, Gao SX, Hubert RS, Hwang M, Hyun L, Kashi S, Kim A, Kim E, Kung J, Martinez SP, Muchhal US, Nguyen DH, O'Brien C, O'Keefe D, Singer K, Vafa O, Vielmetter J, Yoder SC, Dahiyat BI. Steed PM, et al. Among authors: eivazi a. Science. 2003 Sep 26;301(5641):1895-8. doi: 10.1126/science.1081297. Science. 2003. PMID: 14512626
Engineered antibody Fc variants with enhanced effector function.
Lazar GA, Dang W, Karki S, Vafa O, Peng JS, Hyun L, Chan C, Chung HS, Eivazi A, Yoder SC, Vielmetter J, Carmichael DF, Hayes RJ, Dahiyat BI. Lazar GA, et al. Among authors: eivazi a. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4005-10. doi: 10.1073/pnas.0508123103. Epub 2006 Mar 6. Proc Natl Acad Sci U S A. 2006. PMID: 16537476 Free PMC article.
19 results