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Propofol binds and inhibits skeletal muscle ryanodine receptor 1.
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: allen pd. Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048. Epub 2024 Sep 19. Br J Anaesth. 2024. PMID: 39304470 Free PMC article.
Propofol directly binds and inhibits skeletal muscle ryanodine receptor 1 (RyR1).
Joseph TT, Bu W, Haji-Ghassemi O, Chen YS, Woll K, Allen PD, Brannigan G, van Petegem F, Eckenhoff RG. Joseph TT, et al. Among authors: allen pd. bioRxiv [Preprint]. 2024 Jan 12:2024.01.10.575040. doi: 10.1101/2024.01.10.575040. bioRxiv. 2024. Update in: Br J Anaesth. 2024 Nov;133(5):1093-1100. doi: 10.1016/j.bja.2024.06.048 PMID: 38260485 Free PMC article. Updated. Preprint.
Elastic mucus strands impair mucociliary clearance in cystic fibrosis pigs.
Pino-Argumedo MI, Fischer AJ, Hilkin BM, Gansemer ND, Allen PD, Hoffman EA, Stoltz DA, Welsh MJ, Abou Alaiwa MH. Pino-Argumedo MI, et al. Among authors: allen pd. Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2121731119. doi: 10.1073/pnas.2121731119. Epub 2022 Mar 24. Proc Natl Acad Sci U S A. 2022. PMID: 35324331 Free PMC article.
Ryanodine receptor leak triggers fiber Ca2+ redistribution to preserve force and elevate basal metabolism in skeletal muscle.
Lamboley CR, Pearce L, Seng C, Meizoso-Huesca A, Singh DP, Frankish BP, Kaura V, Lo HP, Ferguson C, Allen PD, Hopkins PM, Parton RG, Murphy RM, van der Poel C, Barclay CJ, Launikonis BS. Lamboley CR, et al. Among authors: allen pd. Sci Adv. 2021 Oct 29;7(44):eabi7166. doi: 10.1126/sciadv.abi7166. Epub 2021 Oct 27. Sci Adv. 2021. PMID: 34705503 Free PMC article.
335 results