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Astrocyte-induced Cdk5 expedites breast cancer brain metastasis by suppressing MHC-I expression to evade immune recognition.
Yuzhalin AE, Lowery FJ, Saito Y, Yuan X, Yao J, Duan Y, Ding J, Acharya S, Zhang C, Fajardo A, Chen HN, Wei Y, Sun Y, Zhang L, Xiao Y, Li P, Lorenzi PL, Huse JT, Fan H, Zhao Z, Hung MC, Yu D. Yuzhalin AE, et al. Among authors: saito y. Nat Cell Biol. 2024 Oct;26(10):1773-1789. doi: 10.1038/s41556-024-01509-5. Epub 2024 Sep 20. Nat Cell Biol. 2024. PMID: 39304713
14-3-3ζ turns TGF-β's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2.
Xu J, Acharya S, Sahin O, Zhang Q, Saito Y, Yao J, Wang H, Li P, Zhang L, Lowery FJ, Kuo WL, Xiao Y, Ensor J, Sahin AA, Zhang XH, Hung MC, Zhang JD, Yu D. Xu J, et al. Among authors: saito y. Cancer Cell. 2015 Feb 9;27(2):177-92. doi: 10.1016/j.ccell.2014.11.025. Cancer Cell. 2015. PMID: 25670079 Free PMC article.
The allergy mediator histamine confers resistance to immunotherapy in cancer patients via activation of the macrophage histamine receptor H1.
Li H, Xiao Y, Li Q, Yao J, Yuan X, Zhang Y, Yin X, Saito Y, Fan H, Li P, Kuo WL, Halpin A, Gibbons DL, Yagita H, Zhao Z, Pang D, Ren G, Yee C, Lee JJ, Yu D. Li H, et al. Among authors: saito y. Cancer Cell. 2022 Jan 10;40(1):36-52.e9. doi: 10.1016/j.ccell.2021.11.002. Epub 2021 Nov 24. Cancer Cell. 2022. PMID: 34822775 Free PMC article.
Vitamin E Enhances Cancer Immunotherapy by Reinvigorating Dendritic Cells via Targeting Checkpoint SHP1.
Yuan X, Duan Y, Xiao Y, Sun K, Qi Y, Zhang Y, Ahmed Z, Moiani D, Yao J, Li H, Zhang L, Yuzhalin AE, Li P, Zhang C, Badu-Nkansah A, Saito Y, Liu X, Kuo WL, Ying H, Sun SC, Chang JC, Tainer JA, Yu D. Yuan X, et al. Among authors: saito y. Cancer Discov. 2022 Jul 6;12(7):1742-1759. doi: 10.1158/2159-8290.CD-21-0900. Cancer Discov. 2022. PMID: 35420681 Free PMC article.
Targeting a chemo-induced adaptive signaling circuit confers therapeutic vulnerabilities in pancreatic cancer.
Saito Y, Xiao Y, Yao J, Li Y, Liu W, Yuzhalin AE, Shyu YM, Li H, Yuan X, Li P, Zhang Q, Li Z, Wei Y, Yin X, Zhao J, Kariminia SM, Wu YC, Wang J, Yang J, Xia W, Sun Y, Jho EH, Chiao PJ, Hwang RF, Ying H, Wang H, Zhao Z, Maitra A, Hung MC, DePinho RA, Yu D. Saito Y, et al. Cell Discov. 2024 Oct 29;10(1):109. doi: 10.1038/s41421-024-00720-w. Cell Discov. 2024. PMID: 39468013 Free PMC article.
Suppression of androgen receptor signaling induces prostate cancer migration via activation of the CCL20-CCR6 axis.
Kano H, Izumi K, Hiratsuka K, Toriumi R, Nakagawa R, Aoyama S, Kamijima T, Shimada T, Naito R, Kadomoto S, Iwamoto H, Yaegashi H, Kawaguchi S, Nohara T, Shigehara K, Kadono Y, Saito Y, Nakagawa-Goto K, Yoshioka K, Nakata H, Lin WJ, Mizokami A. Kano H, et al. Among authors: saito y. Cancer Sci. 2023 Apr;114(4):1479-1490. doi: 10.1111/cas.15683. Epub 2022 Dec 18. Cancer Sci. 2023. PMID: 36479732 Free PMC article.
An Institutional Experience of Core Needle Biopsy with Cooperative Implementation by Pathologists and Head and Neck Oncologists in Salivary Gland Carcinoma.
Kobayashi K, Yoshimoto S, Omura G, Matsumoto Y, Sakai A, Eguchi K, Sakai T, Honma Y, Matsumoto F, Kawazu M, Saito Y, Ryo E, Yoshida A, Yatabe Y, Mori T. Kobayashi K, et al. Among authors: saito y. Head Neck Pathol. 2024 Nov 19;18(1):122. doi: 10.1007/s12105-024-01725-3. Head Neck Pathol. 2024. PMID: 39560855
PRDX6 dictates ferroptosis sensitivity by directing cellular selenium utilization.
Ito J, Nakamura T, Toyama T, Chen D, Berndt C, Poschmann G, Mourão ASD, Doll S, Suzuki M, Zhang W, Zheng J, Trümbach D, Yamada N, Ono K, Yazaki M, Kawai Y, Arisawa M, Ohsaki Y, Shirakawa H, Wahida A, Proneth B, Saito Y, Nakagawa K, Mishima E, Conrad M. Ito J, et al. Among authors: saito y. Mol Cell. 2024 Nov 5:S1097-2765(24)00868-2. doi: 10.1016/j.molcel.2024.10.028. Online ahead of print. Mol Cell. 2024. PMID: 39547222
9,684 results