Astegno A - Search Results

1

Evaluating the potential of non-immunosuppressive cyclosporin analogs for targeting Toxoplasma gondii cyclophilin: Insights from structural studies.

Favretto F, Jiménez-Faraco E, Catucci G, Di Matteo A, Travaglini-Allocatelli C, Sadeghi SJ, Dominici P, Hermoso JA, Astegno A. Favretto F, et al. Among authors: astegno a. Protein Sci. 2024 Oct;33(10):e5157. doi: 10.1002/pro.5157. Protein Sci. 2024. PMID: 39312281 Free PMC article.

2

Structural Basis for Cyclosporin Isoform-Specific Inhibition of Cyclophilins from Toxoplasma gondii.

Favretto F, Jiménez-Faraco E, Conter C, Dominici P, Hermoso JA, Astegno A. Favretto F, et al. Among authors: astegno a. ACS Infect Dis. 2023 Feb 10;9(2):365-377. doi: 10.1021/acsinfecdis.2c00566. Epub 2023 Jan 18. ACS Infect Dis. 2023. PMID: 36653744 Free PMC article.

3

Metal binding affinity and structural properties of calmodulin-like protein 14 from Arabidopsis thaliana.

Vallone R, La Verde V, D'Onofrio M, Giorgetti A, Dominici P, Astegno A. Vallone R, et al. Among authors: astegno a. Protein Sci. 2016 Aug;25(8):1461-71. doi: 10.1002/pro.2942. Epub 2016 May 18. Protein Sci. 2016. PMID: 27124620 Free PMC article.

4

Unique substrate specificity of ornithine aminotransferase from Toxoplasma gondii.

Astegno A, Maresi E, Bertoldi M, La Verde V, Paiardini A, Dominici P. Astegno A, et al. Biochem J. 2017 Mar 7;474(6):939-955. doi: 10.1042/BCJ20161021. Biochem J. 2017. PMID: 28126740

5

Distinct Calcium Binding and Structural Properties of Two Centrin Isoforms from Toxoplasma gondii.

Bombardi L, Pedretti M, Conter C, Dominici P, Astegno A. Bombardi L, et al. Among authors: astegno a. Biomolecules. 2020 Aug 4;10(8):1142. doi: 10.3390/biom10081142. Biomolecules. 2020. PMID: 32759683 Free PMC article.

6

The interplay of self-assembly and target binding in centrin 1 from Toxoplasma gondii.

Conter C, Bombardi L, Pedretti M, Favretto F, Di Matteo A, Dominici P, Astegno A. Conter C, et al. Among authors: astegno a. Biochem J. 2021 Jul 16;478(13):2571-2587. doi: 10.1042/BCJ20210295. Biochem J. 2021. PMID: 34114596 Free PMC article.

7

Conformational Plasticity of Centrin 1 from Toxoplasma gondii in Binding to the Centrosomal Protein SFI1.

Bombardi L, Favretto F, Pedretti M, Conter C, Dominici P, Astegno A. Bombardi L, et al. Among authors: astegno a. Biomolecules. 2022 Aug 13;12(8):1115. doi: 10.3390/biom12081115. Biomolecules. 2022. PMID: 36009009 Free PMC article.

8

Structural basis of the inhibition of cystathionine γ-lyase from Toxoplasma gondii by propargylglycine and cysteine.

Fernández-Rodríguez C, Conter C, Oyenarte I, Favretto F, Quintana I, Martinez-Chantar ML, Astegno A, Martínez-Cruz LA. Fernández-Rodríguez C, et al. Among authors: astegno a. Protein Sci. 2023 Apr;32(4):e4619. doi: 10.1002/pro.4619. Protein Sci. 2023. PMID: 36883335 Free PMC article.

9

Key substrate recognition residues in the active site of cystathionine beta-synthase from Toxoplasma gondii.

Conter C, Favretto F, Dominici P, Martinez-Cruz LA, Astegno A. Conter C, et al. Among authors: astegno a. Proteins. 2023 Oct;91(10):1383-1393. doi: 10.1002/prot.26507. Epub 2023 May 10. Proteins. 2023. PMID: 37163386

10

Rapid kinetics of calcium dissociation from plant calmodulin and calmodulin-like proteins and effect of target peptides.

Troilo F, Pedretti M, Travaglini-Allocatelli C, Astegno A, Di Matteo A. Troilo F, et al. Among authors: astegno a. Biochem Biophys Res Commun. 2022 Jan 29;590:103-108. doi: 10.1016/j.bbrc.2021.12.077. Epub 2021 Dec 23. Biochem Biophys Res Commun. 2022. PMID: 34974297

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