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Page 1
Self-sustaining long-term 3D epithelioid cultures reveal drivers of clonal expansion in esophageal epithelium.
Herms A, Fernandez-Antoran D, Alcolea MP, Kalogeropoulou A, Banerjee U, Piedrafita G, Abby E, Valverde-Lopez JA, Ferreira IS, Caseda I, Bejar MT, Dentro SC, Vidal-Notari S, Ong SH, Colom B, Murai K, King C, Mahbubani K, Saeb-Parsy K, Lowe AR, Gerstung M, Jones PH. Herms A, et al. Among authors: fernandez antoran d. Nat Genet. 2024 Oct;56(10):2158-2173. doi: 10.1038/s41588-024-01875-8. Epub 2024 Sep 23. Nat Genet. 2024. PMID: 39313617 Free PMC article.
Organismal metabolism regulates the expansion of oncogenic PIK3CA mutant clones in normal esophagus.
Herms A, Colom B, Piedrafita G, Kalogeropoulou A, Banerjee U, King C, Abby E, Murai K, Caseda I, Fernandez-Antoran D, Ong SH, Hall MWJ, Bryant C, Sood RK, Fowler JC, Pol A, Frezza C, Vanhaesebroeck B, Jones PH. Herms A, et al. Among authors: fernandez antoran d. Nat Genet. 2024 Oct;56(10):2144-2157. doi: 10.1038/s41588-024-01891-8. Epub 2024 Aug 21. Nat Genet. 2024. PMID: 39169259 Free PMC article.
Acute response to pathogens in the early human placenta at single-cell resolution.
Hoo R, Ruiz-Morales ER, Kelava I, Rawat M, Mazzeo CI, Tuck E, Sancho-Serra C, Chelaghma S, Predeus AV, Murray S, Fernandez-Antoran D, Waller RF, Álvarez-Errico D, Lee MCS, Vento-Tormo R. Hoo R, et al. Among authors: fernandez antoran d. Cell Syst. 2024 May 15;15(5):425-444.e9. doi: 10.1016/j.cels.2024.04.002. Epub 2024 May 3. Cell Syst. 2024. PMID: 38703772 Free article.
Mutant clones in normal epithelium outcompete and eliminate emerging tumours.
Colom B, Herms A, Hall MWJ, Dentro SC, King C, Sood RK, Alcolea MP, Piedrafita G, Fernandez-Antoran D, Ong SH, Fowler JC, Mahbubani KT, Saeb-Parsy K, Gerstung M, Hall BA, Jones PH. Colom B, et al. Among authors: fernandez antoran d. Nature. 2021 Oct;598(7881):510-514. doi: 10.1038/s41586-021-03965-7. Epub 2021 Oct 13. Nature. 2021. PMID: 34646013 Free PMC article.
Selection of Oncogenic Mutant Clones in Normal Human Skin Varies with Body Site.
Fowler JC, King C, Bryant C, Hall MWJ, Sood R, Ong SH, Earp E, Fernandez-Antoran D, Koeppel J, Dentro SC, Shorthouse D, Durrani A, Fife K, Rytina E, Milne D, Roshan A, Mahububani K, Saeb-Parsy K, Hall BA, Gerstung M, Jones PH. Fowler JC, et al. Among authors: fernandez antoran d. Cancer Discov. 2021 Feb;11(2):340-361. doi: 10.1158/2159-8290.CD-20-1092. Epub 2020 Oct 21. Cancer Discov. 2021. PMID: 33087317 Free PMC article.
Functional interplay between c-Myc and Max in B lymphocyte differentiation.
Pérez-Olivares M, Trento A, Rodriguez-Acebes S, González-Acosta D, Fernández-Antorán D, Román-García S, Martinez D, López-Briones T, Torroja C, Carrasco YR, Méndez J, Moreno de Alborán I. Pérez-Olivares M, et al. Among authors: fernandez antoran d. EMBO Rep. 2018 Oct;19(10):e45770. doi: 10.15252/embr.201845770. Epub 2018 Aug 20. EMBO Rep. 2018. PMID: 30126925 Free PMC article.