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Page 1
Generic residue numbering of the GAIN domain of adhesion GPCRs.
Seufert F, Pérez-Hernández G, Pándy-Szekeres G, Guixà-González R, Langenhan T, Gloriam DE, Hildebrand PW. Seufert F, et al. Among authors: perez hernandez g. Nat Commun. 2025 Jan 2;16(1):246. doi: 10.1038/s41467-024-55466-6. Nat Commun. 2025. PMID: 39747076 Free PMC article.
Lessons learned during the journey of data: from experiment to model for predicting kinase affinity, selectivity, polypharmacology, and resistance.
López-Ríos de Castro R, Rodríguez-Guerra J, Schaller D, Kimber TB, Taylor C, White JB, Backenköhler M, Payne A, Kaminow B, Pulido I, Singh S, Kramer PL, Pérez-Hernández G, Volkamer A, Chodera JD. López-Ríos de Castro R, et al. Among authors: perez hernandez g. bioRxiv [Preprint]. 2024 Sep 10:2024.09.10.612176. doi: 10.1101/2024.09.10.612176. bioRxiv. 2024. PMID: 39314436 Free PMC article. Preprint.
Mechanistic insights into G-protein coupling with an agonist-bound G-protein-coupled receptor.
Batebi H, Pérez-Hernández G, Rahman SN, Lan B, Kamprad A, Shi M, Speck D, Tiemann JKS, Guixà-González R, Reinhardt F, Stadler PF, Papasergi-Scott MM, Skiniotis G, Scheerer P, Kobilka BK, Mathiesen JM, Liu X, Hildebrand PW. Batebi H, et al. Among authors: perez hernandez g. Nat Struct Mol Biol. 2024 Nov;31(11):1692-1701. doi: 10.1038/s41594-024-01334-2. Epub 2024 Jun 12. Nat Struct Mol Biol. 2024. PMID: 38867113
Time-resolved cryo-EM of G-protein activation by a GPCR.
Papasergi-Scott MM, Pérez-Hernández G, Batebi H, Gao Y, Eskici G, Seven AB, Panova O, Hilger D, Casiraghi M, He F, Maul L, Gmeiner P, Kobilka BK, Hildebrand PW, Skiniotis G. Papasergi-Scott MM, et al. Among authors: perez hernandez g. Nature. 2024 May;629(8014):1182-1191. doi: 10.1038/s41586-024-07153-1. Epub 2024 Mar 13. Nature. 2024. PMID: 38480881 Free PMC article.
Inhibitory to non-inhibitory evolution of the ζ subunit of the F1FO-ATPase of Paracoccus denitrificans and α-proteobacteria as related to mitochondrial endosymbiosis.
Mendoza-Hoffmann F, Yang L, Buratto D, Brito-Sánchez J, Garduño-Javier G, Salinas-López E, Uribe-Álvarez C, Ortega R, Sotelo-Serrano O, Cevallos MÁ, Ramírez-Silva L, Uribe-Carvajal S, Pérez-Hernández G, Celis-Sandoval H, García-Trejo JJ. Mendoza-Hoffmann F, et al. Among authors: perez hernandez g. Front Mol Biosci. 2023 Aug 17;10:1184200. doi: 10.3389/fmolb.2023.1184200. eCollection 2023. Front Mol Biosci. 2023. PMID: 37664184 Free PMC article.
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