Frkic RL - Search Results

1

1.3 Å Crystal Structure of E. coli Peptidyl-Prolyl Isomerase B with Uniform Substitution of Valine by (2S,3S)-4-Fluorovaline Reveals Structure Conservation and Multiple Staggered Rotamers of CH₂F Groups.

Frkic RL, Tan YJ, Maleckis A, Chilton NF, Otting G, Jackson CJ. Frkic RL, et al. Biochemistry. 2024 Oct 15;63(20):2602-2608. doi: 10.1021/acs.biochem.4c00345. Epub 2024 Sep 24. Biochemistry. 2024. PMID: 39316701

2

Increasing the Soluble Expression and Whole-Cell Activity of the Plastic-Degrading Enzyme MHETase through Consensus Design.

Saunders JW, Damry AM, Vongsouthi V, Spence MA, Frkic RL, Gomez C, Yates PA, Matthews DS, Tokuriki N, McLeod MD, Jackson CJ. Saunders JW, et al. Among authors: frkic rl. Biochemistry. 2024 Jul 2;63(13):1663-1673. doi: 10.1021/acs.biochem.4c00165. Epub 2024 Jun 17. Biochemistry. 2024. PMID: 38885634

3

Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.

Frkic RL, Tan YJ, Abdelkader EH, Maleckis A, Tarcoveanu E, Nitsche C, Otting G, Jackson CJ. Frkic RL, et al. Biochemistry. 2024 Jun 4;63(11):1388-1394. doi: 10.1021/acs.biochem.4c00081. Epub 2024 May 14. Biochemistry. 2024. PMID: 38742763

4

Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides.

Smith OB, Frkic RL, Rahman MG, Jackson CJ, Kaczmarski JA. Smith OB, et al. Among authors: frkic rl. Biochemistry. 2024 May 21;63(10):1322-1334. doi: 10.1021/acs.biochem.4c00096. Epub 2024 May 2. Biochemistry. 2024. PMID: 38696389

5

Mononuclear binding and catalytic activity of europium(III) and gadolinium(III) at the active site of the model metalloenzyme phosphotriesterase.

Breeze CW, Nakano Y, Campbell EC, Frkic RL, Lupton DW, Jackson CJ. Breeze CW, et al. Among authors: frkic rl. Acta Crystallogr D Struct Biol. 2024 Apr 1;80(Pt 4):289-298. doi: 10.1107/S2059798324002316. Epub 2024 Mar 21. Acta Crystallogr D Struct Biol. 2024. PMID: 38512071 Free PMC article.

6

A structural basis for the activation of peroxisome proliferator-activated receptor gamma (PPARγ) by perfluorooctanoic acid (PFOA).

Pederick JL, Frkic RL, McDougal DP, Bruning JB. Pederick JL, et al. Among authors: frkic rl. Chemosphere. 2024 Apr;354:141723. doi: 10.1016/j.chemosphere.2024.141723. Epub 2024 Mar 15. Chemosphere. 2024. PMID: 38494006 Free article.

7

PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles.

Frkic RL, Pederick JL, Horsfall AJ, Jovcevski B, Crame EE, Kowalczyk W, Pukala TL, Chang MR, Zheng J, Blayo AL, Abell AD, Kamenecka TM, Harbort JS, Harmer JR, Griffin PR, Bruning JB. Frkic RL, et al. ACS Chem Biol. 2023 May 19;18(5):1115-1123. doi: 10.1021/acschembio.2c00917. Epub 2023 May 5. ACS Chem Biol. 2023. PMID: 37146157

8

Asymmetric Ene-Reduction of α,β-Unsaturated Compounds by F₄₂₀-Dependent Oxidoreductases A Enzymes from Mycobacterium smegmatis.

Kang SW, Antoney J, Frkic RL, Lupton DW, Speight R, Scott C, Jackson CJ. Kang SW, et al. Among authors: frkic rl. Biochemistry. 2023 Feb 7;62(3):873-891. doi: 10.1021/acs.biochem.2c00557. Epub 2022 Dec 5. Biochemistry. 2023. PMID: 36637210

9

Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction.

Abdelkader EH, Qianzhu H, George J, Frkic RL, Jackson CJ, Nitsche C, Otting G, Huber T. Abdelkader EH, et al. Among authors: frkic rl. Angew Chem Int Ed Engl. 2022 Mar 21;61(13):e202114154. doi: 10.1002/anie.202114154. Epub 2022 Feb 11. Angew Chem Int Ed Engl. 2022. PMID: 35102680 Free PMC article.

10

Through-Space Scalar ¹⁹F-¹⁹F Couplings between Fluorinated Noncanonical Amino Acids for the Detection of Specific Contacts in Proteins.

Orton HW, Qianzhu H, Abdelkader EH, Habel EI, Tan YJ, Frkic RL, Jackson CJ, Huber T, Otting G. Orton HW, et al. Among authors: frkic rl. J Am Chem Soc. 2021 Nov 24;143(46):19587-19598. doi: 10.1021/jacs.1c10104. Epub 2021 Nov 15. J Am Chem Soc. 2021. PMID: 34780162

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