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Discovery, Characterization, and Structure of a Cell Active PAD2 Inhibitor Acting through a Novel Allosteric Mechanism.
Byrnes LJ, Choi WY, Balbo P, Banker ME, Chang J, Chen S, Cheng X, Cong Y, Culp J, Di H, Griffor M, Hall J, Meng X, Morgan B, Mousseau JJ, Nicki J, O'Connell T, Ramsey S, Shaginian A, Shanker S, Trujillo J, Wan J, Vincent F, Wright SW, Vajdos F. Byrnes LJ, et al. Among authors: meng x. ACS Chem Biol. 2024 Oct 18;19(10):2186-2197. doi: 10.1021/acschembio.4c00397. Epub 2024 Sep 24. ACS Chem Biol. 2024. PMID: 39316753
Optimization of PROTAC Ternary Complex Using DNA Encoded Library Approach.
Chen Q, Liu C, Wang W, Meng X, Cheng X, Li X, Cai L, Luo L, He X, Qu H, Luo J, Wei H, Gao S, Liu G, Wan J, Israel DI, Li J, Dou D. Chen Q, et al. Among authors: meng x. ACS Chem Biol. 2023 Jan 20;18(1):25-33. doi: 10.1021/acschembio.2c00797. Epub 2023 Jan 6. ACS Chem Biol. 2023. PMID: 36606710 Free PMC article.
Characterization of Specific N-α-Acetyltransferase 50 (Naa50) Inhibitors Identified Using a DNA Encoded Library.
Kung PP, Bingham P, Burke BJ, Chen Q, Cheng X, Deng YL, Dou D, Feng J, Gallego GM, Gehring MR, Grant SK, Greasley S, Harris AR, Maegley KA, Meier J, Meng X, Montano JL, Morgan BA, Naughton BS, Palde PB, Paul TA, Richardson P, Sakata S, Shaginian A, Sonnenburg WK, Subramanyam C, Timofeevski S, Wan J, Yan W, Stewart AE. Kung PP, et al. Among authors: meng x. ACS Med Chem Lett. 2020 Apr 10;11(6):1175-1184. doi: 10.1021/acsmedchemlett.0c00029. eCollection 2020 Jun 11. ACS Med Chem Lett. 2020. PMID: 32550998 Free PMC article.
TQB2450 with or without anlotinib as maintenance treatment in subjects with locally advanced/unresectable non-small cell lung cancer that have not progressed after prior concurrent/sequential chemoradiotherapy (R-ALPS): study protocol for a randomized, double-blind, placebo-controlled, multicenter phase III trial.
Dong B, Chen L, Pang Q, Jiang O, Ge H, Cheng Y, Zhou R, Meng X, Li J, Zhu X, Wang X, Cao Q, Ji Y, Chen M. Dong B, et al. Among authors: meng x. Transl Lung Cancer Res. 2024 Oct 31;13(10):2828-2837. doi: 10.21037/tlcr-24-362. Epub 2024 Oct 28. Transl Lung Cancer Res. 2024. PMID: 39507039 Free PMC article.
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