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Somatic mitochondrial DNA mutations are a source of heterogeneity among primary leukemic cells.
McCastlain K, Welsh C, Ni Y, Ding L, Franco M, Autry R, Sejdiu B, Chang TC, Chen W, Wu H, Pan Q, Gonzalez-Pena V, Schreiner P, Arunachalam S, Joo J, Li B, Shen S, Brady S, Zhang J, Gawad C, Evans W, Babu MM, Khrapko K, Wu G, Yu J, Pounds S, Kundu M. McCastlain K, et al. Among authors: gawad c. medRxiv [Preprint]. 2024 Sep 27:2024.09.26.24314381. doi: 10.1101/2024.09.26.24314381. medRxiv. 2024. PMID: 39398996 Free PMC article. Preprint.
scMicrobe PTA: near complete genomes from single bacterial cells.
Bowers RM, Gonzalez-Pena V, Wardhani K, Goudeau D, Blow MJ, Udwary D, Klein D, Vill AC, Brito IL, Woyke T, Malmstrom RR, Gawad C. Bowers RM, et al. Among authors: gawad c. ISME Commun. 2024 Jul 12;4(1):ycae085. doi: 10.1093/ismeco/ycae085. eCollection 2024 Jan. ISME Commun. 2024. PMID: 39021442 Free PMC article.
scMicrobe PTA: Near Complete Genomes from Single Bacterial Cells.
Bowers RM, Gonzalez-Pena V, Wardhani K, Goudeau D, Blow MJ, Udwary D, Klein D, Vill AC, Brito IL, Woyke T, Malmstrom R, Gawad C. Bowers RM, et al. Among authors: gawad c. bioRxiv [Preprint]. 2024 Jan 31:2024.01.30.577819. doi: 10.1101/2024.01.30.577819. bioRxiv. 2024. Update in: ISME Commun. 2024 Jul 12;4(1):ycae085. doi: 10.1093/ismeco/ycae085 PMID: 38352480 Free PMC article. Updated. Preprint.
Duplex Sequencing Uncovers Recurrent Low-frequency Cancer-associated Mutations in Infant and Childhood KMT2A-rearranged Acute Leukemia.
Pilheden M, Ahlgren L, Hyrenius-Wittsten A, Gonzalez-Pena V, Sturesson H, Hansen Marquart HV, Lausen B, Castor A, Pronk CJ, Barbany G, Pokrovskaja Tamm K, Fogelstrand L, Lohi O, Norén-Nyström U, Asklin J, Chen Y, Song G, Walsh M, Ma J, Zhang J, Saal LH, Gawad C, Hagström-Andersson AK. Pilheden M, et al. Among authors: gawad c. Hemasphere. 2022 Sep 30;6(10):e785. doi: 10.1097/HS9.0000000000000785. eCollection 2022 Oct. Hemasphere. 2022. PMID: 36204688 Free PMC article.
Single-cell genome sequencing of human neurons identifies somatic point mutation and indel enrichment in regulatory elements.
Luquette LJ, Miller MB, Zhou Z, Bohrson CL, Zhao Y, Jin H, Gulhan D, Ganz J, Bizzotto S, Kirkham S, Hochepied T, Libert C, Galor A, Kim J, Lodato MA, Garaycoechea JI, Gawad C, West J, Walsh CA, Park PJ. Luquette LJ, et al. Among authors: gawad c. Nat Genet. 2022 Oct;54(10):1564-1571. doi: 10.1038/s41588-022-01180-2. Epub 2022 Sep 26. Nat Genet. 2022. PMID: 36163278 Free PMC article.
Simultaneous monitoring of disease and microbe dynamics through plasma DNA sequencing in pediatric patients with acute lymphoblastic leukemia.
Barsan V, Xia Y, Klein D, Gonzalez-Pena V, Youssef S, Inaba Y, Mahmud O, Natarajan S, Agarwal V, Pang Y, Autry R, Pui CH, Inaba H, Evans W, Gawad C. Barsan V, et al. Among authors: gawad c. Sci Adv. 2022 Apr 22;8(16):eabj1360. doi: 10.1126/sciadv.abj1360. Epub 2022 Apr 20. Sci Adv. 2022. PMID: 35442732 Free PMC article.
Accurate genomic variant detection in single cells with primary template-directed amplification.
Gonzalez-Pena V, Natarajan S, Xia Y, Klein D, Carter R, Pang Y, Shaner B, Annu K, Putnam D, Chen W, Connelly J, Pruett-Miller S, Chen X, Easton J, Gawad C. Gonzalez-Pena V, et al. Among authors: gawad c. Proc Natl Acad Sci U S A. 2021 Jun 15;118(24):e2024176118. doi: 10.1073/pnas.2024176118. Proc Natl Acad Sci U S A. 2021. PMID: 34099548 Free PMC article.
31 results