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RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.
Tetik-Elsherbiny N, Elsherbiny A, Setya A, Gahn J, Tang Y, Gupta P, Dou Y, Serke H, Wieland T, Dubrac A, Heineke J, Potente M, Cordero J, Ola R, Dobreva G. Tetik-Elsherbiny N, et al. Among authors: heineke j. Nat Cardiovasc Res. 2024 Oct;3(10):1199-1216. doi: 10.1038/s44161-024-00546-5. Epub 2024 Sep 25. Nat Cardiovasc Res. 2024. PMID: 39322771 Free PMC article.
Inter- and Intracellular Signaling Pathways.
Dobreva G, Heineke J. Dobreva G, et al. Among authors: heineke j. Adv Exp Med Biol. 2024;1441:271-294. doi: 10.1007/978-3-031-44087-8_15. Adv Exp Med Biol. 2024. PMID: 38884717 Review.
Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication.
Froese N, Cordero J, Abouissa A, Trogisch FA, Grein S, Szaroszyk M, Wang Y, Gigina A, Korf-Klingebiel M, Bosnjak B, Davenport CF, Wiehlmann L, Geffers R, Riechert E, Jürgensen L, Boileau E, Lin Y, Dieterich C, Förster R, Bauersachs J, Ola R, Dobreva G, Völkers M, Heineke J. Froese N, et al. Among authors: heineke j. iScience. 2022 Feb 23;25(3):103965. doi: 10.1016/j.isci.2022.103965. eCollection 2022 Mar 18. iScience. 2022. PMID: 35281736 Free PMC article.
RNA-Binding Proteins Regulate Post-Transcriptional Responses to TGF-β to Coordinate Function and Mesenchymal Activation of Murine Endothelial Cells.
Wardman R, Keles M, Pachkiv I, Hemanna S, Grein S, Schwarz J, Stein F, Ola R, Dobreva G, Hentze MW, Heineke J. Wardman R, et al. Among authors: heineke j. Arterioscler Thromb Vasc Biol. 2023 Oct;43(10):1967-1989. doi: 10.1161/ATVBAHA.123.319925. Epub 2023 Aug 31. Arterioscler Thromb Vasc Biol. 2023. PMID: 37650327 Free PMC article.
Fibroblast GATA-4 and GATA-6 promote myocardial adaptation to pressure overload by enhancing cardiac angiogenesis.
Dittrich GM, Froese N, Wang X, Kroeger H, Wang H, Szaroszyk M, Malek-Mohammadi M, Cordero J, Keles M, Korf-Klingebiel M, Wollert KC, Geffers R, Mayr M, Conway SJ, Dobreva G, Bauersachs J, Heineke J. Dittrich GM, et al. Among authors: heineke j. Basic Res Cardiol. 2021 Apr 19;116(1):26. doi: 10.1007/s00395-021-00862-y. Basic Res Cardiol. 2021. PMID: 33876316 Free PMC article.
C1q and Tumor Necrosis Factor Related Protein 9 Protects from Diabetic Cardiomyopathy by Alleviating Cardiac Insulin Resistance and Inflammation.
Haustein R, Trogisch FA, Keles M, Hille S, Fuhrmann M, Weinzierl N, Hemanna S, Thackeray J, Dou Y, Zwadlo C, Froese N, Cordero J, Bengel F, Müller OJ, Bauersachs J, Dobreva G, Heineke J. Haustein R, et al. Among authors: heineke j. Cells. 2023 Jan 29;12(3):443. doi: 10.3390/cells12030443. Cells. 2023. PMID: 36766785 Free PMC article.
Endothelial cells drive organ fibrosis in mice by inducing expression of the transcription factor SOX9.
Trogisch FA, Abouissa A, Keles M, Birke A, Fuhrmann M, Dittrich GM, Weinzierl N, Wink E, Cordero J, Elsherbiny A, Martin-Garrido A, Grein S, Hemanna S, Hofmann E, Nicin L, Bibli SI, Airik R, Kispert A, Kist R, Quanchao S, Kürschner SW, Winkler M, Gretz N, Mogler C, Korff T, Koch PS, Dimmeler S, Dobreva G, Heineke J. Trogisch FA, et al. Among authors: heineke j. Sci Transl Med. 2024 Feb 28;16(736):eabq4581. doi: 10.1126/scitranslmed.abq4581. Epub 2024 Feb 28. Sci Transl Med. 2024. PMID: 38416842
Endothelial derived, secreted long non-coding RNAs Gadlor1 and Gadlor2 aggravate cardiac remodeling.
Keles M, Grein S, Froese N, Wirth D, Trogisch FA, Wardman R, Hemanna S, Weinzierl N, Koch PS, Uhlig S, Lomada S, Dittrich GM, Szaroszyk M, Haustein R, Hegermann J, Martin-Garrido A, Bauersachs J, Frank D, Frey N, Bieback K, Cordero J, Dobreva G, Wieland T, Heineke J. Keles M, et al. Among authors: heineke j. Mol Ther Nucleic Acids. 2024 Aug 15;35(3):102306. doi: 10.1016/j.omtn.2024.102306. eCollection 2024 Sep 10. Mol Ther Nucleic Acids. 2024. PMID: 39281699 Free PMC article.
Skeletal muscle derived Musclin protects the heart during pathological overload.
Szaroszyk M, Kattih B, Martin-Garrido A, Trogisch FA, Dittrich GM, Grund A, Abouissa A, Derlin K, Meier M, Holler T, Korf-Klingebiel M, Völker K, Garfias Macedo T, Pablo Tortola C, Boschmann M, Huang N, Froese N, Zwadlo C, Malek Mohammadi M, Luo X, Wagner M, Cordero J, Geffers R, Batkai S, Thum T, Bork N, Nikolaev VO, Müller OJ, Katus HA, El-Armouche A, Kraft T, Springer J, Dobreva G, Wollert KC, Fielitz J, von Haehling S, Kuhn M, Bauersachs J, Heineke J. Szaroszyk M, et al. Among authors: heineke j. Nat Commun. 2022 Jan 10;13(1):149. doi: 10.1038/s41467-021-27634-5. Nat Commun. 2022. PMID: 35013221 Free PMC article.
87 results