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DNA methylation as a new tool for the differential diagnosis between T-LBL and lymphocyte-rich thymoma.
Latiri M, Belhocine M, Smith C, Garnier N, Balducci E, Pinton A, Andrieu GP, Bruneau J, Spicuglia S, Jamain S, Latapie V, de Montpreville VT, Chalabreysse L, Marx A, Girard N, Besse B, Plass C, Gibault L, Badoual C, Macintyre E, Asnafi V, Molina TJ, Touzart A. Latiri M, et al. Among authors: spicuglia s. J Pathol. 2024 Nov;264(3):284-292. doi: 10.1002/path.6346. Epub 2024 Sep 27. J Pathol. 2024. PMID: 39329449
Detecting subtle transcriptomic perturbations induced by lncRNAs knock-down in single-cell CRISPRi screening using a new sparse supervised autoencoder neural network.
Truchi M, Lacoux C, Gille C, Fassy J, Magnone V, Lopes Goncalves R, Girard-Riboulleau C, Manosalva-Pena I, Gautier-Isola M, Lebrigand K, Barbry P, Spicuglia S, Vassaux G, Rezzonico R, Barlaud M, Mari B. Truchi M, et al. Among authors: spicuglia s. Front Bioinform. 2024 Mar 4;4:1340339. doi: 10.3389/fbinf.2024.1340339. eCollection 2024. Front Bioinform. 2024. PMID: 38501112 Free PMC article.
Xenopus tropicalis osteoblast-specific open chromatin regions reveal promoters and enhancers involved in human skeletal phenotypes and shed light on early vertebrate evolution.
Castillo H, Hanna P, Sachs LM, Buisine N, Godoy F, Gilbert C, Aguilera F, Muñoz D, Boisvert C, Debiais-Thibaud M, Wan J, Spicuglia S, Marcellini S. Castillo H, et al. Among authors: spicuglia s. Cells Dev. 2024 Sep;179:203924. doi: 10.1016/j.cdev.2024.203924. Epub 2024 Apr 29. Cells Dev. 2024. PMID: 38692409
Neonatal CD4+ T cells have a characteristic transcriptome and epigenome and respond to TCR stimulation with proliferation and yet a limited immune response.
Kempis-Calanis LA, Rodríguez-Jorge O, Gutiérrez-Reyna DY, Ventura-Martínez CJ, Spicuglia S, Medina-Rivera A, Thieffry D, González A, Santana MA. Kempis-Calanis LA, et al. Among authors: spicuglia s. J Leukoc Biol. 2024 Jun 28;116(1):64-76. doi: 10.1093/jleuko/qiad162. J Leukoc Biol. 2024. PMID: 38146769
PHF6-altered T-ALL Harbor Epigenetic Repressive Switch at Bivalent Promoters and Respond to 5-Azacitidine and Venetoclax.
Pinton A, Courtois L, Doublet C, Cabannes-Hamy A, Andrieu G, Smith C, Balducci E, Cieslak A, Touzart A, Simonin M, Lhéritier V, Huguet F, Balsat M, Dombret H, Rousselot P, Spicuglia S, Macintyre E, Boissel N, Asnafi V. Pinton A, et al. Among authors: spicuglia s. Clin Cancer Res. 2024 Jan 5;30(1):94-105. doi: 10.1158/1078-0432.CCR-23-2159. Clin Cancer Res. 2024. PMID: 37889114
G4access identifies G-quadruplexes and their associations with open chromatin and imprinting control regions.
Esnault C, Magat T, Zine El Aabidine A, Garcia-Oliver E, Cucchiarini A, Bouchouika S, Lleres D, Goerke L, Luo Y, Verga D, Lacroix L, Feil R, Spicuglia S, Mergny JL, Andrau JC. Esnault C, et al. Among authors: spicuglia s. Nat Genet. 2023 Aug;55(8):1359-1369. doi: 10.1038/s41588-023-01437-4. Epub 2023 Jul 3. Nat Genet. 2023. PMID: 37400615 Free article.
IL-7 receptor expression is frequent in T-cell acute lymphoblastic leukemia and predicts sensitivity to JAK inhibition.
Courtois L, Cabannes-Hamy A, Kim R, Delecourt M, Pinton A, Charbonnier G, Feroul M, Smith C, Tueur G, Pivert C, Balducci E, Simonin M, Angel LH, Spicuglia S, Boissel N, Andrieu GP, Asnafi V, Rousselot P, Lhermitte L. Courtois L, et al. Among authors: spicuglia s. Blood. 2023 Jul 13;142(2):158-171. doi: 10.1182/blood.2022017948. Blood. 2023. PMID: 37023368 Free article.
92 results