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Page 1
Ancient developmental genes underlie evolutionary novelties in walking fish.
Herbert AL, Allard CAH, McCoy MJ, Wucherpfennig JI, Krueger SP, Chen HI, Gourlay AN, Jackson KD, Abbo LA, Bennett SH, Sears JD, Rhyne AL, Bellono NW, Kingsley DM. Herbert AL, et al. Among authors: sears jd. Curr Biol. 2024 Oct 7;34(19):4339-4348.e6. doi: 10.1016/j.cub.2024.08.042. Epub 2024 Sep 26. Curr Biol. 2024. PMID: 39332403 Free PMC article.
The genetic basis of novel trait gain in walking fish.
Herbert AL, Allard CA, McCoy MJ, Wucherpfennig JI, Krueger SP, Chen HI, Gourlay AN, Jackson KD, Abbo LA, Bennett SH, Sears JD, Rhyne AL, Bellono NW, Kingsley DM. Herbert AL, et al. Among authors: sears jd. bioRxiv [Preprint]. 2023 Oct 14:2023.10.14.562356. doi: 10.1101/2023.10.14.562356. bioRxiv. 2023. Update in: Curr Biol. 2024 Oct 7;34(19):4339-4348.e6. doi: 10.1016/j.cub.2024.08.042. PMID: 37873105 Free PMC article. Updated. Preprint.
Identification of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Tse EG, Stashko MA, Li K, Norris-Drouin JL, Herring LE, Mordant AL, Webb TS, Mills CA, Barker NK, Streblow ZJ, Perveen S, Arrowsmith CH, Couñago RM, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise MT, Willson TM, Popov KI, Pearce KH. Merten EM, et al. Among authors: sears jd. Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2409166121. doi: 10.1073/pnas.2409166121. Epub 2024 Oct 10. Proc Natl Acad Sci U S A. 2024. PMID: 39388272
Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Antialphavirus Activity.
Ghoshal A, Asressu KH, Hossain MA, Brown PJ, Nandakumar M, Vala A, Merten EM, Sears JD, Law I, Burdick JE, Morales NL, Perveen S, Pearce KH, Popov KI, Moorman NJ, Heise MT, Willson TM. Ghoshal A, et al. Among authors: sears jd. J Med Chem. 2024 Sep 26;67(18):16505-16532. doi: 10.1021/acs.jmedchem.4c01346. Epub 2024 Sep 5. J Med Chem. 2024. PMID: 39235978 Free PMC article.
Structure Activity of β-Amidomethyl Vinyl Sulfones as Covalent Inhibitors of Chikungunya nsP2 Cysteine Protease with Anti-alphavirus Activity.
Ghoshal A, Asressu KH, Hossain MA, Brown PJ, Merten EM, Sears JD, Perveen S, Pearce KH, Popov KI, Moorman NJ, Heise MT, Willson TM. Ghoshal A, et al. Among authors: sears jd. bioRxiv [Preprint]. 2024 Jun 13:2024.06.12.598722. doi: 10.1101/2024.06.12.598722. bioRxiv. 2024. Update in: J Med Chem. 2024 Sep 26;67(18):16505-16532. doi: 10.1021/acs.jmedchem.4c01346. PMID: 38915519 Free PMC article. Updated. Preprint.
IL3-Driven T Cell-Basophil Crosstalk Enhances Antitumor Immunity.
Wei J, Mayberry CL, Lv X, Hu F, Khan T, Logan NA, Wilson JJ, Sears JD, Chaussabel D, Chang CH. Wei J, et al. Among authors: sears jd. Cancer Immunol Res. 2024 Jul 2;12(7):822-839. doi: 10.1158/2326-6066.CIR-23-0851. Cancer Immunol Res. 2024. PMID: 38739030
Discovery of a cell-active chikungunya virus nsP2 protease inhibitor using a covalent fragment-based screening approach.
Merten EM, Sears JD, Leisner TM, Hardy PB, Ghoshal A, Hossain MA, Asressu KH, Brown PJ, Stashko MA, Herring L, Mordant AL, Webb TS, Mills CA, Barker NK, Streblow ZJ, Perveen S, Arrowsmith C, Arnold JJ, Cameron CE, Streblow DN, Moorman NJ, Heise M, Willson TM, Popov K, Pearce KH. Merten EM, et al. Among authors: sears jd. bioRxiv [Preprint]. 2024 May 23:2024.03.22.586341. doi: 10.1101/2024.03.22.586341. bioRxiv. 2024. Update in: Proc Natl Acad Sci U S A. 2024 Oct 15;121(42):e2409166121. doi: 10.1073/pnas.2409166121. PMID: 38562906 Free PMC article. Updated. Preprint.
Transcriptome Analysis Reveals Organ-Specific Effects of 2-Deoxyglucose Treatment in Healthy Mice.
Wells AE, Wilson JJ, Sears JD, Wei J, Heuer S, Pandey R, Costa MW, Kaczorowski CC, Roopenian DC, Chang CH, Carter GW. Wells AE, et al. Among authors: sears jd. bioRxiv [Preprint]. 2023 May 12:2023.04.24.537717. doi: 10.1101/2023.04.24.537717. bioRxiv. 2023. Update in: PLoS One. 2024 Mar 7;19(3):e0299595. doi: 10.1371/journal.pone.0299595. PMID: 37162857 Free PMC article. Updated. Preprint.
31 results