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Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy.
Joers V, Murray BC, McLaughlin C, Oliver D, Staley HE, Coronado J, Achat-Mendes C, Golshani S, Kelly SD, Goodson M, Lee D, Manfredsson FP, Moore Ii BM, Tansey MG. Joers V, et al. Among authors: manfredsson fp. J Neuroinflammation. 2024 Sep 27;21(1):240. doi: 10.1186/s12974-024-03221-5. J Neuroinflammation. 2024. PMID: 39334169 Free PMC article.
Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy.
Joers V, Murray BC, McLaughlin C, Oliver D, Staley H, Coronado J, Achat-Mendes C, Golshani S, Kelly SD, Goodson M, Lee D, Manfredsson FP, Moore BM 2nd, Tansey MG. Joers V, et al. Among authors: manfredsson fp. bioRxiv [Preprint]. 2024 Mar 23:2023.08.25.554814. doi: 10.1101/2023.08.25.554814. bioRxiv. 2024. Update in: J Neuroinflammation. 2024 Sep 27;21(1):240. doi: 10.1186/s12974-024-03221-5. PMID: 38562842 Free PMC article. Updated. Preprint.
Gene Therapy to Modulate Alpha-Synuclein in Synucleinopathies.
Sandoval IM, Marmion DJ, Meyers KT, Manfredsson FP. Sandoval IM, et al. Among authors: manfredsson fp. J Parkinsons Dis. 2021;11(s2):S189-S197. doi: 10.3233/JPD-212679. J Parkinsons Dis. 2021. PMID: 34092656 Free PMC article. Review.
Sequential or Simultaneous Injection of Preformed Fibrils and AAV Overexpression of Alpha-Synuclein Are Equipotent in Producing Relevant Pathology and Behavioral Deficits.
Negrini M, Tomasello G, Davidsson M, Fenyi A, Adant C, Hauser S, Espa E, Gubinelli F, Manfredsson FP, Melki R, Heuer A. Negrini M, et al. Among authors: manfredsson fp. J Parkinsons Dis. 2022;12(4):1133-1153. doi: 10.3233/JPD-212555. J Parkinsons Dis. 2022. PMID: 35213388 Free PMC article.
In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration.
Gorbatyuk OS, Li S, Nash K, Gorbatyuk M, Lewin AS, Sullivan LF, Mandel RJ, Chen W, Meyers C, Manfredsson FP, Muzyczka N. Gorbatyuk OS, et al. Among authors: manfredsson fp. Mol Ther. 2010 Aug;18(8):1450-7. doi: 10.1038/mt.2010.115. Epub 2010 Jun 15. Mol Ther. 2010. PMID: 20551914 Free PMC article.
102 results