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Comprehensive antitumor immune response boosted by dual inhibition of SUMOylation and MEK in MYC-expressing KRAS-mutant cancers.
Kotani H, Yamano T, Boucher JC, Sato S, Sakaguchi H, Fukuda K, Nishiyama A, Yamashita K, Ohtsubo K, Takeuchi S, Nishiuchi T, Oshima H, Oshima M, Davila ML, Yano S. Kotani H, et al. Among authors: davila ml. Exp Hematol Oncol. 2024 Sep 27;13(1):94. doi: 10.1186/s40164-024-00563-x. Exp Hematol Oncol. 2024. PMID: 39334463 Free PMC article.
4-1BB enhancement of CAR T function requires NF-κB and TRAFs.
Li G, Boucher JC, Kotani H, Park K, Zhang Y, Shrestha B, Wang X, Guan L, Beatty N, Abate-Daga D, Davila ML. Li G, et al. Among authors: davila ml. JCI Insight. 2018 Sep 20;3(18):e121322. doi: 10.1172/jci.insight.121322. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232281 Free PMC article.
Tumor Microenvironment Composition and Severe Cytokine Release Syndrome (CRS) Influence Toxicity in Patients with Large B-Cell Lymphoma Treated with Axicabtagene Ciloleucel.
Faramand R, Jain M, Staedtke V, Kotani H, Bai R, Reid K, Lee SB, Spitler K, Wang X, Cao B, Pinilla J, Lazaryan A, Khimani F, Shah B, Chavez JC, Nishihori T, Mishra A, Mullinax J, Gonzalez R, Hussaini M, Dam M, Brandjes BD, Bachmeier CA, Anasetti C, Locke FL, Davila ML. Faramand R, et al. Among authors: davila ml. Clin Cancer Res. 2020 Sep 15;26(18):4823-4831. doi: 10.1158/1078-0432.CCR-20-1434. Epub 2020 Jul 15. Clin Cancer Res. 2020. PMID: 32669372 Free PMC article. Clinical Trial.
CD28 Costimulatory Domain-Targeted Mutations Enhance Chimeric Antigen Receptor T-cell Function.
Boucher JC, Li G, Kotani H, Cabral ML, Morrissey D, Lee SB, Spitler K, Beatty NJ, Cervantes EV, Shrestha B, Yu B, Kazi A, Wang X, Sebti SM, Davila ML. Boucher JC, et al. Among authors: davila ml. Cancer Immunol Res. 2021 Jan;9(1):62-74. doi: 10.1158/2326-6066.CIR-20-0253. Epub 2020 Nov 13. Cancer Immunol Res. 2021. PMID: 33188139 Free PMC article.
Chimeric Antigen Receptor Design Today and Tomorrow.
Boucher JC, Davila ML. Boucher JC, et al. Among authors: davila ml. Cancer J. 2021 Mar-Apr 01;27(2):92-97. doi: 10.1097/PPO.0000000000000514. Cancer J. 2021. PMID: 33750067 Review.
102 results