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A single-nucleotide resolution capillary gel electrophoresis workflow for poly(A) tail characterization in the development of mRNA therapeutics and vaccines.
Di Grandi D, Dayeh DM, Kaur K, Chen Y, Henderson S, Moon Y, Bhowmick A, Ihnat PM, Fu Y, Muthusamy K, Palackal N, Pyles EA. Di Grandi D, et al. Among authors: pyles ea. J Pharm Biomed Anal. 2023 Nov 30;236:115692. doi: 10.1016/j.jpba.2023.115692. Epub 2023 Sep 2. J Pharm Biomed Anal. 2023. PMID: 37696189 Free article.
Comparison of capillary electrophoresis-based methods for the analytical characterization of purity and stability of in vitro transcribed mRNA.
Mantri P, Juneja B, Henderson S, Koufos E, Moon Y, Dayeh DM, Di Grandi D, Fu Y, Muthusamy K, Ihnat PM, Palackal N, Pyles EA. Mantri P, et al. Among authors: pyles ea. J Pharm Biomed Anal. 2024 Oct 15;249:116352. doi: 10.1016/j.jpba.2024.116352. Epub 2024 Jul 14. J Pharm Biomed Anal. 2024. PMID: 39029354 Free article.
Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes.
MacDonald DA, Martin J, Muthusamy KK, Luo JK, Pyles E, Rafique A, Huang T, Potocky T, Liu Y, Cao J, Bono F, Delesque N, Savi P, Francis J, Amirkhosravi A, Meyer T, Romano C, Glinka M, Yancopoulos GD, Stahl N, Wiegand SJ, Papadopoulos N. MacDonald DA, et al. Angiogenesis. 2016 Jul;19(3):389-406. doi: 10.1007/s10456-016-9515-8. Epub 2016 May 27. Angiogenesis. 2016. PMID: 27234973 Free PMC article.
23 results