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Page 1
Chemical genetic analysis of enoxolone inhibition of Clostridioides difficile toxin production reveals adenine deaminase and ATP synthase as antivirulence targets.
Marreddy RKR, Phelps GA, Churion K, Picker J, Powell R, Cherian PT, Bowling JJ, Stephan CC, Lee RE, Hurdle JG. Marreddy RKR, et al. Among authors: phelps ga. J Biol Chem. 2024 Nov;300(11):107839. doi: 10.1016/j.jbc.2024.107839. Epub 2024 Sep 27. J Biol Chem. 2024. PMID: 39343002 Free PMC article.
Discovery and Characterization of the Antimetabolite Action of Thioacetamide-Linked 1,2,3-Triazoles as Disruptors of Cysteine Biosynthesis in Gram-Negative Bacteria.
Wallace MJ, Dharuman S, Fernando DM, Reeve SM, Gee CT, Yao J, Griffith EC, Phelps GA, Wright WC, Elmore JM, Lee RB, Chen T, Lee RE. Wallace MJ, et al. Among authors: phelps ga. ACS Infect Dis. 2020 Mar 13;6(3):467-478. doi: 10.1021/acsinfecdis.9b00406. Epub 2020 Jan 13. ACS Infect Dis. 2020. PMID: 31887254 Free PMC article.
Azaindole Based Potentiator of Antibiotics against Gram-Negative Bacteria.
Sharma S, Rao R, Reeve SM, Phelps GA, Bharatham N, Katagihallimath N, Ramachandran V, Raveendran S, Sarma M, Nath A, Thomas T, Manickam D, Nagaraj S, Balasubramanian V, Lee RE, Hameed P S, Datta S. Sharma S, et al. Among authors: phelps ga. ACS Infect Dis. 2021 Nov 12;7(11):3009-3024. doi: 10.1021/acsinfecdis.1c00171. Epub 2021 Oct 26. ACS Infect Dis. 2021. PMID: 34699190
Identification of Inhibitors of Fungal Fatty Acid Biosynthesis.
DeJarnette C, Meyer CJ, Jenner AR, Butts A, Peters T, Cheramie MN, Phelps GA, Vita NA, Loudon-Hossler VC, Lee RE, Palmer GE. DeJarnette C, et al. Among authors: phelps ga. ACS Infect Dis. 2021 Dec 10;7(12):3210-3223. doi: 10.1021/acsinfecdis.1c00404. Epub 2021 Nov 17. ACS Infect Dis. 2021. PMID: 34786940 Free PMC article.
Development of 2nd generation aminomethyl spectinomycins that overcome native efflux in Mycobacterium abscessus.
Phelps GA, Cheramie MN, Fernando DM, Selchow P, Meyer CJ, Waidyarachchi SL, Dharuman S, Liu J, Meuli M, Molin MD, Killam BY, Murphy PA, Reeve SM, Wilt LA, Anderson SM, Yang L, Lee RB, Temrikar ZH, Lukka PB, Meibohm B, Polikanov YS, Hobbie SN, Böttger EC, Sander P, Lee RE. Phelps GA, et al. Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2314101120. doi: 10.1073/pnas.2314101120. Epub 2024 Jan 2. Proc Natl Acad Sci U S A. 2024. PMID: 38165935 Free PMC article.
Synthesis and antibacterial action of 3',6'-disubstituted spectinomycins.
Dharuman S, Phelps GA, Dunn CM, Wilt LA, Murphy PA, Lee RB, Snoke HE, Selchow P, Haldimann K, Böttger EC, Hobbie SN, Sander P, Lee RE. Dharuman S, et al. Among authors: phelps ga. J Antibiot (Tokyo). 2024 Sep;77(9):577-588. doi: 10.1038/s41429-024-00750-2. Epub 2024 Jun 18. J Antibiot (Tokyo). 2024. PMID: 38890386 Free PMC article.
Correction: Synthesis and antibacterial action of 3',6'-disubstituted spectinomycins.
Dharuman S, Phelps GA, Dunn CM, Wilt LA, Murphy PA, Lee RB, Snoke HE, Selchow P, Haldimann K, Böttger EC, Hobbie SN, Sander P, Lee RE. Dharuman S, et al. Among authors: phelps ga. J Antibiot (Tokyo). 2024 Oct 11. doi: 10.1038/s41429-024-00777-5. Online ahead of print. J Antibiot (Tokyo). 2024. PMID: 39394258 No abstract available.
14 results