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Anti-metabolite chemotherapy increases LAG-3 expressing tumor-infiltrating lymphocytes which can be targeted by combination immune checkpoint blockade.
Principe N, Phung AL, Stevens KLP, Elaskalani O, Wylie B, Tilsed CM, Sheikh F, Orozco Morales ML, Kidman J, Marcq E, Fisher SA, Nowak AK, McDonnell AM, Lesterhuis WJ, Chee J. Principe N, et al. Among authors: elaskalani o. J Immunother Cancer. 2024 Sep 28;12(9):e008568. doi: 10.1136/jitc-2023-008568. J Immunother Cancer. 2024. PMID: 39343508 Free PMC article.
Local therapy with combination TLR agonists stimulates systemic anti-tumor immunity and sensitizes tumors to immune checkpoint blockade.
Rwandamuriye FX, Wang T, Zhang H, Elaskalani O, Kuster J, Ye X, Vitali B, Schreurs J, Orozco Morales ML, Norret M, Evans CW, Zemek RM, Iyer KS, Lesterhuis WJ, Wylie B. Rwandamuriye FX, et al. Among authors: elaskalani o. Oncoimmunology. 2024 Aug 22;13(1):2395067. doi: 10.1080/2162402X.2024.2395067. eCollection 2024. Oncoimmunology. 2024. PMID: 39188754 Free PMC article.
Molecular and cellular mechanisms of chemoresistance in pancreatic cancer.
Adamska A, Elaskalani O, Emmanouilidi A, Kim M, Abdol Razak NB, Metharom P, Falasca M. Adamska A, et al. Among authors: elaskalani o. Adv Biol Regul. 2018 May;68:77-87. doi: 10.1016/j.jbior.2017.11.007. Epub 2017 Nov 22. Adv Biol Regul. 2018. PMID: 29221990 Review.
Targeting Platelets for the Treatment of Cancer.
Elaskalani O, Berndt MC, Falasca M, Metharom P. Elaskalani O, et al. Cancers (Basel). 2017 Jul 22;9(7):94. doi: 10.3390/cancers9070094. Cancers (Basel). 2017. PMID: 28737696 Free PMC article. Review.
11 results