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Early detection of ovarian cancer using cell-free DNA fragmentomes and protein biomarkers.
Medina JE, Annapragada AV, Lof P, Short S, Bartolomucci AL, Mathios D, Koul S, Niknafs N, Noe M, Foda ZH, Bruhm DC, Hruban C, Vulpescu NA, Jung E, Dua R, Canzoniero JV, Cristiano S, Adleff V, Symecko H, van den Broek D, Sokoll LJ, Baylin SB, Press MF, Slamon DJ, Konecny GE, Therkildsen C, Carvalho B, Meijer GA, Andersen CL, Domchek SM, Drapkin R, Scharpf RB, Phallen J, Lok CAR, Velculescu VE. Medina JE, et al. Among authors: van den broek d. Cancer Discov. 2024 Sep 30. doi: 10.1158/2159-8290.CD-24-0393. Online ahead of print. Cancer Discov. 2024. PMID: 39345137
Diagnostic Strategies toward Clinical Implementation of Liquid Biopsy RAS/BRAF Circulating Tumor DNA Analyses in Patients with Metastatic Colorectal Cancer.
van 't Erve I, Greuter MJE, Bolhuis K, Vessies DCL, Leal A, Vink GR, van den Broek D, Velculescu VE, Punt CJA, Meijer GA, Coupé VMH, Fijneman RJA. van 't Erve I, et al. Among authors: van den broek d. J Mol Diagn. 2020 Dec;22(12):1430-1437. doi: 10.1016/j.jmoldx.2020.09.002. Epub 2020 Sep 19. J Mol Diagn. 2020. PMID: 32961317 Free article.
Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions.
Hummelink K, Muller M, Linders TC, van der Noort V, Nederlof PM, Baas P, Burgers S, Smit EF, Meijer GA, van den Heuvel MM, van den Broek D, Monkhorst K. Hummelink K, et al. Among authors: van den heuvel mm, van den broek d, van der noort v. ERJ Open Res. 2019 Mar 25;5(1):00016-2019. doi: 10.1183/23120541.00016-2019. eCollection 2019 Feb. ERJ Open Res. 2019. PMID: 30918895 Free PMC article.
KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases.
van 't Erve I, Wesdorp NJ, Medina JE, Ferreira L, Leal A, Huiskens J, Bolhuis K, van Waesberghe JTM, Swijnenburg RJ, van den Broek D, Velculescu VE, Kazemier G, Punt CJA, Meijer GA, Fijneman RJA. van 't Erve I, et al. Among authors: van den broek d, van waesberghe jtm. JCO Precis Oncol. 2021 Nov 17;5:PO.21.00223. doi: 10.1200/PO.21.00223. eCollection 2021. JCO Precis Oncol. 2021. PMID: 34820593 Free PMC article.
Evaluating the effectiveness of pre-operative diagnosis of ovarian cancer using minimally invasive liquid biopsies by combining serum human epididymis protein 4 and cell-free DNA in patients with an ovarian mass.
Gaillard DHK, Lof P, Sistermans EA, Mokveld T, Horlings HM, Mom CH, Reinders MJT, Amant F, van den Broek D, Wessels LFA, Lok CAR; HE4 Study Group; Study group. Gaillard DHK, et al. Among authors: van den broek d. Int J Gynecol Cancer. 2024 May 6;34(5):713-721. doi: 10.1136/ijgc-2023-005073. Int J Gynecol Cancer. 2024. PMID: 38388177
Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study.
Schraa SJ, van Rooijen KL, van der Kruijssen DEW, Rubio Alarcón C, Phallen J, Sausen M, Simmons J, Coupé VMH, van Grevenstein WMU, Elias S, Verkooijen HM, Laclé MM, Bosch LJW, van den Broek D, Meijer GA, Velculescu VE, Fijneman RJA, Vink GR, Koopman M; PLCRC-MEDOCC group. Schraa SJ, et al. Among authors: van rooijen kl, van der kruijssen dew, van den broek d, van grevenstein wmu. BMC Cancer. 2020 Aug 20;20(1):790. doi: 10.1186/s12885-020-07252-y. BMC Cancer. 2020. PMID: 32819390 Free PMC article.
An Automated Correction Algorithm (ALPACA) for ddPCR Data Using Adaptive Limit of Blank and Correction of False Positive Events Improves Specificity of Mutation Detection.
Vessies DCL, Linders TC, Lanfermeijer M, Ramkisoensing KL, van der Noort V, Schouten RD, Meijer GA, van den Heuvel MM, Monkhorst K, van den Broek D. Vessies DCL, et al. Among authors: van den heuvel mm, van den broek d, van der noort v. Clin Chem. 2021 Jul 6;67(7):959-967. doi: 10.1093/clinchem/hvab040. Clin Chem. 2021. PMID: 33842952
Detection of tumor-derived cell-free DNA from colorectal cancer peritoneal metastases in plasma and peritoneal fluid.
Van't Erve I, Rovers KP, Constantinides A, Bolhuis K, Wassenaar EC, Lurvink RJ, Huysentruyt CJ, Snaebjornsson P, Boerma D, van den Broek D, Buffart TE, Lahaye MJ, Aalbers AG, Kok NF, Meijer GA, Punt CJ, Kranenburg O, de Hingh IH, Fijneman RJ. Van't Erve I, et al. Among authors: van den broek d. J Pathol Clin Res. 2021 May;7(3):203-208. doi: 10.1002/cjp2.207. Epub 2021 Feb 26. J Pathol Clin Res. 2021. PMID: 33635598 Free PMC article.
Can serum human epididymis protein 4 (HE4) support the decision to refer a patient with an ovarian mass to an oncology hospital?
Lof P, van de Vrie R, Korse CM, van Gent MDJM, Mom CH, Rosier-van Dunné FMF, van Baal WM, Verhoeve HR, Hermsen BBJ, Verbruggen MB, Hemelaar M, van de Swaluw AMG, Knipscheer HC, Huirne JAF, Westenberg SM, van der Noort V, Amant F, van den Broek D, Lok CAR. Lof P, et al. Among authors: van baal wm, van gent mdjm, van de vrie r, van den broek d, van de swaluw amg, van der noort v. Gynecol Oncol. 2022 Aug;166(2):284-291. doi: 10.1016/j.ygyno.2022.05.025. Epub 2022 Jun 8. Gynecol Oncol. 2022. PMID: 35688656
98 results