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Page 1
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.
Bauman AA, Sarathy JP, Kaya F, Massoudi LM, Scherman MS, Hastings C, Liu J, Xie M, Brooks EJ, Ramey ME, Jones IL, Benedict ND, Maclaughlin MR, Miller-Dawson JA, Waidyarachchi SL, Butler MM, Bowlin TL, Zimmerman MD, Lenaerts AJ, Meibohm B, Gonzalez-Juarrero M, Lyons MA, Dartois V, Lee RE, Robertson GT. Bauman AA, et al. Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0071624. doi: 10.1128/aac.00716-24. Epub 2024 Sep 30. Antimicrob Agents Chemother. 2024. PMID: 39345140 Free PMC article.
Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model.
Ramey ME, Kaya F, Bauman AA, Massoudi LM, Sarathy JP, Zimmerman MD, Scott DWL, Job AM, Miller-Dawson JA, Podell BK, Lyons MA, Dartois V, Lenaerts AJ, Robertson GT. Ramey ME, et al. Among authors: bauman aa. Antimicrob Agents Chemother. 2023 Nov 15;67(11):e0059723. doi: 10.1128/aac.00597-23. Epub 2023 Oct 4. Antimicrob Agents Chemother. 2023. PMID: 37791784 Free PMC article.
Lung microenvironments harbor Mycobacterium tuberculosis phenotypes with distinct treatment responses.
Walter ND, Ernest JP, Dide-Agossou C, Bauman AA, Ramey ME, Rossmassler K, Massoudi LM, Pauly S, Al Mubarak R, Voskuil MI, Kaya F, Sarathy JP, Zimmerman MD, Dartois V, Podell BK, Savic RM, Robertson GT. Walter ND, et al. Among authors: bauman aa. Antimicrob Agents Chemother. 2023 Sep 19;67(9):e0028423. doi: 10.1128/aac.00284-23. Epub 2023 Aug 11. Antimicrob Agents Chemother. 2023. PMID: 37565762 Free PMC article.
Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis.
Bauman AA, Sarathy JP, Kaya F, Massoudi LM, Scherman MS, Hastings C, Liu J, Xie M, Brooks EJ, Ramey ME, Jones IL, Benedict ND, Maclaughlin MR, Miller-Dawson JA, Waidyarachchi SL, Butler MM, Bowlin TL, Zimmerman MD, Lenaerts AJ, Meibohm B, Gonzalez-Juarrero M, Lyons MA, Dartois V, Lee RE, Robertson GT. Bauman AA, et al. bioRxiv [Preprint]. 2024 May 13:2024.05.13.593953. doi: 10.1101/2024.05.13.593953. bioRxiv. 2024. Update in: Antimicrob Agents Chemother. 2024 Nov 6;68(11):e0071624. doi: 10.1128/aac.00716-24 PMID: 38798577 Free PMC article. Updated. Preprint.
Combination of Mycobacterium tuberculosis RS Ratio and CFU Improves the Ability of Murine Efficacy Experiments to Distinguish between Drug Treatments.
Dide-Agossou C, Bauman AA, Ramey ME, Rossmassler K, Al Mubarak R, Pauly S, Voskuil MI, Garcia-Cremades M, Savic RM, Nahid P, Moore CM, Tasneen R, Nuermberger EL, Robertson GT, Walter ND. Dide-Agossou C, et al. Among authors: bauman aa. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0231021. doi: 10.1128/aac.02310-21. Epub 2022 Mar 21. Antimicrob Agents Chemother. 2022. PMID: 35311519 Free PMC article.
Mycobacterium tuberculosis precursor rRNA as a measure of treatment-shortening activity of drugs and regimens.
Walter ND, Born SEM, Robertson GT, Reichlen M, Dide-Agossou C, Ektnitphong VA, Rossmassler K, Ramey ME, Bauman AA, Ozols V, Bearrows SC, Schoolnik G, Dolganov G, Garcia B, Musisi E, Worodria W, Huang L, Davis JL, Nguyen NV, Nguyen HV, Nguyen ATV, Phan H, Wilusz C, Podell BK, Sanoussi ND, de Jong BC, Merle CS, Affolabi D, McIlleron H, Garcia-Cremades M, Maidji E, Eshun-Wilson F, Aguilar-Rodriguez B, Karthikeyan D, Mdluli K, Bansbach C, Lenaerts AJ, Savic RM, Nahid P, Vásquez JJ, Voskuil MI. Walter ND, et al. Among authors: bauman aa. Nat Commun. 2021 May 18;12(1):2899. doi: 10.1038/s41467-021-22833-6. Nat Commun. 2021. PMID: 34006838 Free PMC article.
Transcriptional adaptation of drug-tolerant Mycobacterium tuberculosis in mice.
Wynn EA, Dide-Agossou C, Reichlen M, Rossmassler K, Al Mubarak R, Reid JJ, Tabor ST, Born SEM, Ransom MR, Davidson RM, Walton KN, Benoit JB, Hoppers A, Bauman AA, Massoudi LM, Dolganov G, Nahid P, Voskuil MI, Robertson GT, Moore CM, Walter ND. Wynn EA, et al. Among authors: bauman aa. bioRxiv [Preprint]. 2023 Mar 8:2023.03.06.531356. doi: 10.1101/2023.03.06.531356. bioRxiv. 2023. PMID: 36945388 Free PMC article. Preprint.
Transcriptional adaptation of Mycobacterium tuberculosis that survives prolonged multi-drug treatment in mice.
Wynn EA, Dide-Agossou C, Reichlen M, Rossmassler K, Al Mubarak R, Reid JJ, Tabor ST, Born SEM, Ransom MR, Davidson RM, Walton KN, Benoit JB, Hoppers A, Loy DE, Bauman AA, Massoudi LM, Dolganov G, Strong M, Nahid P, Voskuil MI, Robertson GT, Moore CM, Walter ND. Wynn EA, et al. Among authors: bauman aa. mBio. 2023 Dec 19;14(6):e0236323. doi: 10.1128/mbio.02363-23. Epub 2023 Oct 31. mBio. 2023. PMID: 37905920 Free PMC article.
16 results