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YAP/TAZ signaling in allantois-derived cells is required for placental vascularization.
Gao S, Thillaikumaran T, Dominguez MH, Giang W, Hayes K, Chen X, Pace J, Bockman J, Jathan D, Sung D, Narayan S, Frankfurter M, Mericko-Ishizuka P, Yang J, Castro M, Potente M, Kahn ML. Gao S, et al. Among authors: kahn ml. bioRxiv [Preprint]. 2024 Sep 16:2024.09.15.613151. doi: 10.1101/2024.09.15.613151. bioRxiv. 2024. PMID: 39345443 Free PMC article. Preprint.
SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice.
Tang AT, Buchholz DW, Szigety KM, Imbhiaka B, Gao S, Frankfurter M, Wang M, Yang J, Hewins P, Mericko-Ishizuka P, Adrian Leu N, Sterling S, Monreal IA, Sahler J, August A, Zhu X, Jurado KA, Xu M, Morrisey EE, Millar SE, Aguilar HC, Kahn ML. Tang AT, et al. Among authors: kahn ml. bioRxiv [Preprint]. 2021 Dec 7:2021.12.04.471245. doi: 10.1101/2021.12.04.471245. bioRxiv. 2021. PMID: 34909769 Free PMC article. Preprint.
Endothelial SARS-CoV-2 infection is not the underlying cause of COVID19-associated vascular pathology in mice.
Gao S, Tang AT, Wang M, Buchholz DW, Imbiakha B, Yang J, Chen X, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, August A, Jurado KA, Morrisey EE, Aguilar-Carreno H, Kahn ML. Gao S, et al. Among authors: kahn ml. bioRxiv [Preprint]. 2023 Jul 24:2023.07.24.550352. doi: 10.1101/2023.07.24.550352. bioRxiv. 2023. Update in: Front Cardiovasc Med. 2023 Sep 26;10:1266276. doi: 10.3389/fcvm.2023.1266276. PMID: 37546961 Free PMC article. Updated. Preprint.
mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice.
Li L, Ren AA, Gao S, Su YS, Yang J, Bockman J, Mericko-Ishizuka P, Griffin J, Shenkar R, Alcazar R, Moore T, Lightle R, DeBiasse D, Awad IA, Marchuk DA, Kahn ML, Burkhardt JK. Li L, et al. Among authors: kahn ml. Stroke. 2023 Nov;54(11):2906-2917. doi: 10.1161/STROKEAHA.123.044108. Epub 2023 Sep 25. Stroke. 2023. PMID: 37746705 Free PMC article.
Cell-autonomous requirement for ACE2 across organs in lethal mouse SARS-CoV-2 infection.
Tang AT, Buchholz DW, Szigety KM, Imbiakha B, Gao S, Frankfurter M, Wang M, Yang J, Hewins P, Mericko-Ishizuka P, Leu NA, Sterling S, Monreal IA, Sahler J, August A, Zhu X, Jurado KA, Xu M, Morrisey EE, Millar SE, Aguilar HC, Kahn ML. Tang AT, et al. Among authors: kahn ml. PLoS Biol. 2023 Feb 6;21(2):e3001989. doi: 10.1371/journal.pbio.3001989. eCollection 2023 Feb. PLoS Biol. 2023. PMID: 36745682 Free PMC article.
Lymph flow regulates collecting lymphatic vessel maturation in vivo.
Sweet DT, Jiménez JM, Chang J, Hess PR, Mericko-Ishizuka P, Fu J, Xia L, Davies PF, Kahn ML. Sweet DT, et al. Among authors: kahn ml. J Clin Invest. 2015 Aug 3;125(8):2995-3007. doi: 10.1172/JCI79386. Epub 2015 Jul 27. J Clin Invest. 2015. PMID: 26214523 Free PMC article.
PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism.
Ren AA, Snellings DA, Su YS, Hong CC, Castro M, Tang AT, Detter MR, Hobson N, Girard R, Romanos S, Lightle R, Moore T, Shenkar R, Benavides C, Beaman MM, Müller-Fielitz H, Chen M, Mericko P, Yang J, Sung DC, Lawton MT, Ruppert JM, Schwaninger M, Körbelin J, Potente M, Awad IA, Marchuk DA, Kahn ML. Ren AA, et al. Among authors: kahn ml. Nature. 2021 Jun;594(7862):271-276. doi: 10.1038/s41586-021-03562-8. Epub 2021 Apr 28. Nature. 2021. PMID: 33910229 Free PMC article.
254 results