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Advancing Clinical Response Against Glioblastoma: Evaluating SHP1705 CRY2 Activator Efficacy in Preclinical Models and Safety in Phase I Trials.
Chan P, Nagai Y, Wu Q, Hovsepyan A, Mkhitaryan S, Wang J, Karapetyan G, Kamenecka T, Solt LA, Cope J, Moats RA, Hirota T, Rich JN, Kay SA. Chan P, et al. Among authors: wu q. bioRxiv [Preprint]. 2024 Sep 21:2024.09.17.613520. doi: 10.1101/2024.09.17.613520. bioRxiv. 2024. PMID: 39345648 Free PMC article. Preprint.
Elevated invasive potential of glioblastoma stem cells.
Cheng L, Wu Q, Guryanova OA, Huang Z, Huang Q, Rich JN, Bao S. Cheng L, et al. Among authors: wu q. Biochem Biophys Res Commun. 2011 Mar 25;406(4):643-8. doi: 10.1016/j.bbrc.2011.02.123. Epub 2011 Mar 1. Biochem Biophys Res Commun. 2011. PMID: 21371437 Free PMC article.
Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models.
Dermawan JK, Hitomi M, Silver DJ, Wu Q, Sandlesh P, Sloan AE, Purmal AA, Gurova KV, Rich JN, Lathia JD, Stark GR, Venere M. Dermawan JK, et al. Among authors: wu q. Cancer Res. 2016 Apr 15;76(8):2432-42. doi: 10.1158/0008-5472.CAN-15-2162. Epub 2016 Feb 26. Cancer Res. 2016. PMID: 26921329 Free PMC article.
Nicotinamide metabolism regulates glioblastoma stem cell maintenance.
Jung J, Kim LJ, Wang X, Wu Q, Sanvoranart T, Hubert CG, Prager BC, Wallace LC, Jin X, Mack SC, Rich JN. Jung J, et al. Among authors: wu q. JCI Insight. 2017 May 18;2(10):e90019. doi: 10.1172/jci.insight.90019. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515364 Free PMC article.
Chromatin remodeler HELLS maintains glioma stem cells through E2F3 and MYC.
Zhang G, Dong Z, Prager BC, Kim LJ, Wu Q, Gimple RC, Wang X, Bao S, Hamerlik P, Rich JN. Zhang G, et al. Among authors: wu q. JCI Insight. 2019 Apr 4;4(7):e126140. doi: 10.1172/jci.insight.126140. eCollection 2019 Apr 4. JCI Insight. 2019. PMID: 30779712 Free PMC article.
Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock.
Dong Z, Zhang G, Qu M, Gimple RC, Wu Q, Qiu Z, Prager BC, Wang X, Kim LJY, Morton AR, Dixit D, Zhou W, Huang H, Li B, Zhu Z, Bao S, Mack SC, Chavez L, Kay SA, Rich JN. Dong Z, et al. Among authors: wu q. Cancer Discov. 2019 Nov;9(11):1556-1573. doi: 10.1158/2159-8290.CD-19-0215. Epub 2019 Aug 27. Cancer Discov. 2019. PMID: 31455674 Free PMC article.
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