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Page 1
PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance.
Chen Z, Inague A, Kaushal K, Fazeli G, Schilling D, Xavier da Silva TN, Dos Santos AF, Cheytan T, Freitas FP, Yildiz U, Viviani LG, Lima RS, Pinz MP, Medeiros I, Iijima TS, Alegria TGP, Pereira da Silva R, Diniz LR, Weinzweig S, Klein-Seetharaman J, Trumpp A, Mañas A, Hondal R, Bartenhagen C, Fischer M, Shimada BK, Seale LA, Chillon TS, Fabiano M, Schomburg L, Schweizer U, Netto LE, Meotti FC, Dick TP, Alborzinia H, Miyamoto S, Friedmann Angeli JP. Chen Z, et al. Among authors: bartenhagen c. Mol Cell. 2024 Dec 5;84(23):4645-4659.e9. doi: 10.1016/j.molcel.2024.10.027. Epub 2024 Nov 14. Mol Cell. 2024. PMID: 39547224 Free article.
METTL3/MYCN cooperation drives neural crest differentiation and provides therapeutic vulnerability in neuroblastoma.
Thombare K, Vaid R, Pucci P, Ihrmark Lundberg K, Ayyalusamy R, Baig MH, Mendez A, Burgos-Panadero R, Höppner S, Bartenhagen C, Sjövall D, Rehan AA, Dattatraya Nale S, Djos A, Martinsson T, Jaako P, Dong JJ, Kogner P, Johnsen JI, Fischer M, Turner SD, Mondal T. Thombare K, et al. Among authors: bartenhagen c. EMBO J. 2024 Dec;43(24):6310-6335. doi: 10.1038/s44318-024-00299-8. Epub 2024 Nov 11. EMBO J. 2024. PMID: 39528654 Free PMC article.
TERT Expression and Clinical Outcome in Pulmonary Carcinoids.
Werr L, Bartenhagen C, Rosswog C, Cartolano M, Voegele C, Sexton-Oates A, Di Genova A, Ernst A, Kahlert Y, Hemstedt N, Höppner S, Mansuet Lupo A, Pelosi G, Brcic L, Papotti M, George J, Bosco G, Quaas A, Tang LH, Robzyk K, Kadota K, Roh MS, Fanaroff RE, Falcon CJ, Büttner R, Lantuejoul S, Rekhtman N, Rudin CM, Travis WD, Alcala N, Fernandez-Cuesta L, Foll M, Peifer M, Thomas RK, Fischer M; Lung NEN Network. Werr L, et al. Among authors: bartenhagen c. J Clin Oncol. 2024 Sep 30:JCO2302708. doi: 10.1200/JCO.23.02708. Online ahead of print. J Clin Oncol. 2024. PMID: 39348606
PRDX6 contributes to selenocysteine metabolism and ferroptosis resistance.
Chen Z, Inague A, Kaushal K, Fazeli G, N Xavier da Silva T, Ferreira Dos Santos A, Cheytan T, Porto Freitas F, Yildiz U, Gasparello Viviani L, Santiago Lima R, Peglow Pinz M, Medeiros I, Geronimo Pires Alegria T, Pereira da Silva R, Regina Diniz L, Weinzweig S, Klein-Seetharaman J, Trumpp A, Manas A, Hondal R, Fischer M, Bartenhagen C, Shimada BK, Seale LA, Fabiano M, Schweizer U, Netto LE, Meotti FC, Alborzinia H, Miyamoto S, Friedmann Angeli JP. Chen Z, et al. Among authors: bartenhagen c. bioRxiv [Preprint]. 2024 Jun 6:2024.06.04.597364. doi: 10.1101/2024.06.04.597364. bioRxiv. 2024. Update in: Mol Cell. 2024 Dec 5;84(23):4645-4659.e9. doi: 10.1016/j.molcel.2024.10.027 PMID: 38895225 Free PMC article. Updated. Preprint.
METTL3 drives telomere targeting of TERRA lncRNA through m6A-dependent R-loop formation: a therapeutic target for ALT-positive neuroblastoma.
Vaid R, Thombare K, Mendez A, Burgos-Panadero R, Djos A, Jachimowicz D, Lundberg KI, Bartenhagen C, Kumar N, Tümmler C, Sihlbom C, Fransson S, Johnsen JI, Kogner P, Martinsson T, Fischer M, Mondal T. Vaid R, et al. Among authors: bartenhagen c. Nucleic Acids Res. 2024 Mar 21;52(5):2648-2671. doi: 10.1093/nar/gkad1242. Nucleic Acids Res. 2024. PMID: 38180812 Free PMC article.
Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer.
Malchers F, Nogova L, van Attekum MH, Maas L, Brägelmann J, Bartenhagen C, Girard L, Bosco G, Dahmen I, Michels S, Weeden CE, Scheel AH, Meder L, Golfmann K, Schuldt P, Siemanowski J, Rehker J, Merkelbach-Bruse S, Menon R, Gautschi O, Heuckmann JM, Brambilla E, Asselin-Labat ML, Persigehl T, Minna JD, Walczak H, Ullrich RT, Fischer M, Reinhardt HC, Wolf J, Büttner R, Peifer M, George J, Thomas RK. Malchers F, et al. Among authors: bartenhagen c. J Clin Invest. 2023 Nov 1;133(21):e170217. doi: 10.1172/JCI170217. J Clin Invest. 2023. PMID: 37606995 Free PMC article.
LRP8-mediated selenocysteine uptake is a targetable vulnerability in MYCN-amplified neuroblastoma.
Alborzinia H, Chen Z, Yildiz U, Freitas FP, Vogel FCE, Varga JP, Batani J, Bartenhagen C, Schmitz W, Büchel G, Michalke B, Zheng J, Meierjohann S, Girardi E, Espinet E, Flórez AF, Dos Santos AF, Aroua N, Cheytan T, Haenlin J, Schlicker L, Xavier da Silva TN, Przybylla A, Zeisberger P, Superti-Furga G, Eilers M, Conrad M, Fabiano M, Schweizer U, Fischer M, Schulze A, Trumpp A, Friedmann Angeli JP. Alborzinia H, et al. Among authors: bartenhagen c. EMBO Mol Med. 2023 Aug 7;15(8):e18014. doi: 10.15252/emmm.202318014. Epub 2023 Jul 12. EMBO Mol Med. 2023. PMID: 37435859 Free PMC article.
Genomic ALK alterations in primary and relapsed neuroblastoma.
Rosswog C, Fassunke J, Ernst A, Schömig-Markiefka B, Merkelbach-Bruse S, Bartenhagen C, Cartolano M, Ackermann S, Theissen J, Blattner-Johnson M, Jones B, Schramm K, Altmüller J, Nürnberg P, Ortmann M, Berthold F, Peifer M, Büttner R, Westermann F, Schulte JH, Simon T, Hero B, Fischer M. Rosswog C, et al. Among authors: bartenhagen c. Br J Cancer. 2023 Apr;128(8):1559-1571. doi: 10.1038/s41416-023-02208-y. Epub 2023 Feb 17. Br J Cancer. 2023. PMID: 36807339 Free PMC article.
Reliable assessment of telomere maintenance mechanisms in neuroblastoma.
Meeser A, Bartenhagen C, Werr L, Hellmann AM, Kahlert Y, Hemstedt N, Nürnberg P, Altmüller J, Ackermann S, Hero B, Simon T, Peifer M, Fischer M, Rosswog C. Meeser A, et al. Among authors: bartenhagen c. Cell Biosci. 2022 Sep 24;12(1):160. doi: 10.1186/s13578-022-00896-2. Cell Biosci. 2022. PMID: 36153564 Free PMC article.
Telomerase-targeting compounds Imetelstat and 6-thio-dG act synergistically with chemotherapy in high-risk neuroblastoma models.
Fischer-Mertens J, Otte F, Roderwieser A, Rosswog C, Kahlert Y, Werr L, Hellmann AM, Berding M, Chiu B, Bartenhagen C, Fischer M. Fischer-Mertens J, et al. Among authors: bartenhagen c. Cell Oncol (Dordr). 2022 Oct;45(5):991-1003. doi: 10.1007/s13402-022-00702-8. Epub 2022 Aug 12. Cell Oncol (Dordr). 2022. PMID: 35953764 Free PMC article.
48 results