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Page 1
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
Chatterjee S, Naeli P, Onar O, Simms N, Garzia A, Hackett A, Coyle K, Harris Snell P, McGirr T, Sawant TN, Dang K, Stoichkova ZV, Azam Y, Saunders MP, Braun M, Alain T, Tuschl T, McDade SS, Longley DB, Gkogkas CG, Adrain C, Knight JRP, Jafarnejad SM. Chatterjee S, et al. Among authors: knight jrp. Nucleic Acids Res. 2024 Nov 11;52(20):12534-12548. doi: 10.1093/nar/gkae849. Nucleic Acids Res. 2024. PMID: 39351862 Free PMC article.
Correction to: Brf1 loss and not overexpression disrupts tissues homeostasis in the intestine, liver and pancreas.
Liko D, Mitchell L, Campbell KJ, Ridgway RA, Jones C, Dudek K, King A, Bryson S, Stevenson D, Blyth K, Strathdee D, Morton JP, Bird TG, Knight JRP, Willis AE, Sansom OJ. Liko D, et al. Among authors: knight jrp. Cell Death Differ. 2024 Sep;31(9):1235-1237. doi: 10.1038/s41418-024-01344-z. Cell Death Differ. 2024. PMID: 39095545 Free article. No abstract available.
Tuning protein synthesis for cancer therapy.
Knight JRP, Sansom OJ. Knight JRP, et al. Mol Cell Oncol. 2021 Feb 22;8(2):1884034. doi: 10.1080/23723556.2021.1884034. Mol Cell Oncol. 2021. PMID: 33855169 Free PMC article.
Translation initiation in cancer at a glance.
Smith RCL, Kanellos G, Vlahov N, Alexandrou C, Willis AE, Knight JRP, Sansom OJ. Smith RCL, et al. Among authors: knight jrp. J Cell Sci. 2021 Jan 13;134(1):jcs248476. doi: 10.1242/jcs.248476. J Cell Sci. 2021. PMID: 33441326 Review.
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer.
Najumudeen AK, Ceteci F, Fey SK, Hamm G, Steven RT, Hall H, Nikula CJ, Dexter A, Murta T, Race AM, Sumpton D, Vlahov N, Gay DM, Knight JRP, Jackstadt R, Leach JDG, Ridgway RA, Johnson ER, Nixon C, Hedley A, Gilroy K, Clark W, Malla SB, Dunne PD, Rodriguez-Blanco G, Critchlow SE, Mrowinska A, Malviya G, Solovyev D, Brown G, Lewis DY, Mackay GM, Strathdee D, Tardito S, Gottlieb E; CRUK Rosetta Grand Challenge Consortium; Takats Z, Barry ST, Goodwin RJA, Bunch J, Bushell M, Campbell AD, Sansom OJ. Najumudeen AK, et al. Among authors: knight jrp. Nat Genet. 2021 Jan;53(1):16-26. doi: 10.1038/s41588-020-00753-3. Epub 2021 Jan 7. Nat Genet. 2021. PMID: 33414552
MNK Inhibition Sensitizes KRAS-Mutant Colorectal Cancer to mTORC1 Inhibition by Reducing eIF4E Phosphorylation and c-MYC Expression.
Knight JRP, Alexandrou C, Skalka GL, Vlahov N, Pennel K, Officer L, Teodosio A, Kanellos G, Gay DM, May-Wilson S, Smith EM, Najumudeen AK, Gilroy K, Ridgway RA, Flanagan DJ, Smith RCL, McDonald L, MacKay C, Cheasty A, McArthur K, Stanway E, Leach JD, Jackstadt R, Waldron JA, Campbell AD, Vlachogiannis G, Valeri N, Haigis KM, Sonenberg N, Proud CG, Jones NP, Swarbrick ME, McKinnon HJ, Faller WJ, Le Quesne J, Edwards J, Willis AE, Bushell M, Sansom OJ. Knight JRP, et al. Cancer Discov. 2021 May;11(5):1228-1247. doi: 10.1158/2159-8290.CD-20-0652. Epub 2020 Dec 16. Cancer Discov. 2021. PMID: 33328217 Free PMC article.
28 results