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Page 1
Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome.
Barettino A, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Guerrero CR, Espinosa FM, Carmona RM, Blanco Y, Dorado B, Torroja C, Sánchez-Cabo F, Quintas A, Benguría A, Dopazo A, García R, Benedicto I, Andrés V. Barettino A, et al. Among authors: carmona rm. J Clin Invest. 2024 Oct 1;134(22):e173448. doi: 10.1172/JCI173448. J Clin Invest. 2024. PMID: 39352768 Free PMC article.
Endothelial cell-specific progerin expression does not cause cardiovascular alterations and premature death.
Benedicto I, Hamczyk MR, Nevado RM, Barettino A, Carmona RM, Espinós-Estévez C, Gonzalo P, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Dorado B, Andrés V. Benedicto I, et al. Among authors: carmona rm. Aging Cell. 2024 Oct 31:e14389. doi: 10.1111/acel.14389. Online ahead of print. Aging Cell. 2024. PMID: 39479939 Free article.
Polμ deficiency increases resistance to oxidative damage and delays liver aging.
Escudero B, Lucas D, Albo C, Dhup S, Bacher JW, Sánchez-Muñoz A, Fernández M, Rivera-Torres J, Carmona RM, Fuster E, Carreiro C, Bernad R, González MA, Andrés V, Blanco L, Roche E, Fabregat I, Samper E, Bernad A. Escudero B, et al. Among authors: carmona rm. PLoS One. 2014 Apr 1;9(4):e93074. doi: 10.1371/journal.pone.0093074. eCollection 2014. PLoS One. 2014. PMID: 24691161 Free PMC article.
Bmi1-Progenitor Cell Ablation Impairs the Angiogenic Response to Myocardial Infarction.
Herrero D, Cañón S, Pelacho B, Salvador-Bernáldez M, Aguilar S, Pogontke C, Carmona RM, Salvador JM, Perez-Pomares JM, Klein OD, Prósper F, Jimenez-Borreguero LJ, Bernad A. Herrero D, et al. Among authors: carmona rm. Arterioscler Thromb Vasc Biol. 2018 Sep;38(9):2160-2173. doi: 10.1161/ATVBAHA.118.310778. Arterioscler Thromb Vasc Biol. 2018. PMID: 29930004 Free PMC article.
Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells.
Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V. Benedicto I, et al. Among authors: carmona rm. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2400752121. doi: 10.1073/pnas.2400752121. Epub 2024 Apr 22. Proc Natl Acad Sci U S A. 2024. PMID: 38648484 Free PMC article.
Deconstructing Noncovalent Kelch-like ECH-Associated Protein 1 (Keap1) Inhibitors into Fragments to Reconstruct New Potent Compounds.
Pallesen JS, Narayanan D, Tran KT, Solbak SMØ, Marseglia G, Sørensen LME, Høj LJ, Munafò F, Carmona RMC, Garcia AD, Desu HL, Brambilla R, Johansen TN, Popowicz GM, Sattler M, Gajhede M, Bach A. Pallesen JS, et al. Among authors: carmona rmc. J Med Chem. 2021 Apr 22;64(8):4623-4661. doi: 10.1021/acs.jmedchem.0c02094. Epub 2021 Apr 5. J Med Chem. 2021. PMID: 33818106 Free article.
A Comparative Assessment Study of Known Small-Molecule Keap1-Nrf2 Protein-Protein Interaction Inhibitors: Chemical Synthesis, Binding Properties, and Cellular Activity.
Tran KT, Pallesen JS, Solbak SMØ, Narayanan D, Baig A, Zang J, Aguayo-Orozco A, Carmona RMC, Garcia AD, Bach A. Tran KT, et al. Among authors: carmona rmc. J Med Chem. 2019 Sep 12;62(17):8028-8052. doi: 10.1021/acs.jmedchem.9b00723. Epub 2019 Aug 27. J Med Chem. 2019. PMID: 31411465 Free article.
11 results