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A human DCC variant causing mirror movement disorder reveals that the WAVE regulatory complex mediates axon guidance by netrin-1-DCC.
Chaudhari K, Zhang K, Yam PT, Zang Y, Kramer DA, Gagnon S, Schlienger S, Calabretta S, Michaud JF, Collins M, Wang J, Srour M, Chen B, Charron F, Bashaw GJ. Chaudhari K, et al. Among authors: kramer da. Sci Signal. 2024 Oct;17(856):eadk2345. doi: 10.1126/scisignal.adk2345. Epub 2024 Oct 1. Sci Signal. 2024. PMID: 39353037 Free PMC article.
Arf GTPase activates the WAVE regulatory complex through a distinct binding site.
Yang S, Tang Y, Liu Y, Brown AJ, Schaks M, Ding B, Kramer DA, Mietkowska M, Ding L, Alekhina O, Billadeau DD, Chowdhury S, Wang J, Rottner K, Chen B. Yang S, et al. Among authors: kramer da. Sci Adv. 2022 Dec 14;8(50):eadd1412. doi: 10.1126/sciadv.add1412. Epub 2022 Dec 14. Sci Adv. 2022. PMID: 36516255 Free PMC article.
Structural basis for Retriever-SNX17 assembly and endosomal sorting.
Singla A, Boesch DJ, Fung HYJ, Ngoka C, Enriquez AS, Song R, Kramer DA, Han Y, Banarer E, Lemoff A, Juneja P, Billadeau DD, Bai X, Chen Z, Turer EE, Burstein E, Chen B. Singla A, et al. Among authors: kramer da. Nat Commun. 2024 Nov 25;15(1):10193. doi: 10.1038/s41467-024-54583-6. Nat Commun. 2024. PMID: 39587083 Free PMC article.
Structural Organization of the Retriever-CCC Endosomal Recycling Complex.
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E. Boesch DJ, et al. Among authors: kramer da. bioRxiv [Preprint]. 2023 Jun 7:2023.06.06.543888. doi: 10.1101/2023.06.06.543888. bioRxiv. 2023. Update in: Nat Struct Mol Biol. 2024 Jun;31(6):910-924. doi: 10.1038/s41594-023-01184-4 PMID: 37333304 Free PMC article. Updated. Preprint.
Structural Organization of the Retriever-CCC Endosomal Recycling Complex.
Boesch DJ, Singla A, Han Y, Kramer DA, Liu Q, Suzuki K, Juneja P, Zhao X, Long X, Medlyn MJ, Billadeau DD, Chen Z, Chen B, Burstein E. Boesch DJ, et al. Among authors: kramer da. Res Sq [Preprint]. 2023 Jun 16:rs.3.rs-3026818. doi: 10.21203/rs.3.rs-3026818/v1. Res Sq. 2023. Update in: Nat Struct Mol Biol. 2024 Jun;31(6):910-924. doi: 10.1038/s41594-023-01184-4 PMID: 37397996 Free PMC article. Updated. Preprint.
42 results