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Page 1
Standardization through education of molecular pathology: a spotlight on the European Masters in Molecular Pathology.
Ilié M, Lake V, de Alava E, Bonin S, Chlebowski S, Delort A, Dequeker E, Al-Dieri R, Diepstra A, Carpén O, Eloy C, Fassina A, Fend F, Fernandez PL, Gorkiewicz G, Heeke S, Henrique R, Hoefler G, Huertas P, Hummel M, Kashofer K, van der Laak J, de Pablos RM, Schmitt F, Schuuring E, Stanta G, Timens W, Westphalen B, Hofman P. Ilié M, et al. Among authors: timens w. Virchows Arch. 2024 Nov;485(5):761-775. doi: 10.1007/s00428-024-03933-2. Epub 2024 Oct 2. Virchows Arch. 2024. PMID: 39354109 Review.
Developments in predictive biomarker testing and targeted therapy in advanced stage non-small cell lung cancer and their application across European countries.
de Jager VD, Timens W, Bayle A, Botling J, Brcic L, Büttner R, Fernandes MGO, Havel L, Hochmair MJ, Hofman P, Janssens A, Johansson M, van Kempen L, Kern I, Lopez-Rios F, Lüchtenborg M, Machado JC, Mohorcic K, Paz-Ares L, Popat S, Ryška A, Taniere P, Wolf J, Schuuring E, van der Wekken AJ. de Jager VD, et al. Among authors: timens w. Lancet Reg Health Eur. 2024 Mar 1;38:100838. doi: 10.1016/j.lanepe.2024.100838. eCollection 2024 Mar. Lancet Reg Health Eur. 2024. PMID: 38476742 Free PMC article. Review.
Future perspective for the application of predictive biomarker testing in advanced stage non-small cell lung cancer.
de Jager VD, Timens W, Bayle A, Botling J, Brcic L, Büttner R, Fernandes MGO, Havel L, Hochmair M, Hofman P, Janssens A, van Kempen L, Kern I, Machado JC, Mohorčič K, Popat S, Ryška A, Wolf J, Schuuring E, van der Wekken AJ. de Jager VD, et al. Among authors: timens w. Lancet Reg Health Eur. 2024 Mar 1;38:100839. doi: 10.1016/j.lanepe.2024.100839. eCollection 2024 Mar. Lancet Reg Health Eur. 2024. PMID: 38476751 Free PMC article. Review.
Therapeutic drug monitoring guided dosing versus standard dosing of alectinib in advanced ALK positive non-small cell lung cancer patients: Study protocol for an international, multicenter phase IV randomized controlled trial (ADAPT ALEC).
Meertens M, Muntinghe-Wagenaar MB, Sikkema BJ, Lopez-Yurda M, Retèl VP, Paats MS, Ter Heine R, Schuuring E, Timens W, Touw DJ, van Boven JFM, de Langen AJ, Hashemi SMS, Hendriks LEL, Croes S, van den Heuvel MM, Dingemans AC, Mathijssen RHJ, Smit EF, Huitema ADR, Steeghs N, van der Wekken AJ. Meertens M, et al. Among authors: timens w. Front Oncol. 2023 Mar 9;13:1136221. doi: 10.3389/fonc.2023.1136221. eCollection 2023. Front Oncol. 2023. PMID: 36969063 Free PMC article.
A reproducibility study on invasion in small pulmonary adenocarcinoma according to the WHO and a modified classification, supported by biomarkers.
Thunnissen E, Blaauwgeers H, Filipello F, Lissenberg-Witte B, Minami Y, Noguchi M, Quesne JL, Papotti MG, Flieder DB, Pelosi G, Sansano I, Berezowska S, Ryška A, Brcic L, Motoi N, Nakatani Y, Kuempers C, Hofman P, Hofman V, Dale VG, Rossi G, Ambrosi F, Matsubara D, Ishikawa Y, Weynand B, Calabrese F, Pezzuto F, Kern I, Nicholson S, Mutka A, Dacic S, Beasley MB, Arrigoni G, Timens W, Ooft M, Brinkhuis M, Bulkmans N, Britstra R, Vreuls W, Jones KD, von der Thüsen JH, Hager H, Perner S, Moore D, Leonte DG, Al-Janabi S, Schønau A, Neumann O, Kluck K, Ourailidis I, Ball M, Budczies J, Kazdal D, Stenzinger A. Thunnissen E, et al. Among authors: timens w. Lung Cancer. 2024 Dec 19;199:108060. doi: 10.1016/j.lungcan.2024.108060. Online ahead of print. Lung Cancer. 2024. PMID: 39793325 Free article.
The soluble receptor for advanced glycation end products is potentially predictive of pulmonary arterial hypertension in systemic sclerosis.
Atzeni IM, Al-Adwi Y, Doornbos-van der Meer B, Roozendaal C, Stel A, van Goor H, Gan CT, Dickinson M, Timens W, Smit AJ, Westra J, Mulder DJ. Atzeni IM, et al. Among authors: timens w. Front Immunol. 2023 Jun 20;14:1189257. doi: 10.3389/fimmu.2023.1189257. eCollection 2023. Front Immunol. 2023. PMID: 37409127 Free PMC article.
The additional diagnostic value of virtual bronchoscopy navigation in patients with pulmonary nodules - The NAVIGATOR study.
Hiddinga BI, Slebos DJ, David Koster T, Hijmering-Kappelle LBM, Hiltermann TJN, Kievit H, van der Wekken AJ, de Jonge G, Vliegenthart R, Van De Wauwer C, Timens W, Bensch F. Hiddinga BI, et al. Among authors: timens w. Lung Cancer. 2023 Mar;177:37-43. doi: 10.1016/j.lungcan.2023.01.012. Epub 2023 Jan 24. Lung Cancer. 2023. PMID: 36708592 Free article.
Improved Annotation of Asthma Gene Variants with Cell Type Deconvolution of Nasal and Lung Expression-Quantitative Trait Loci.
El-Husseini ZW, Karp T, Lan A, Gillett TE, Qi C, Khalenkow D, van der Molen T, Brightling C, Papi A, Rabe KF, Siddiqui S, Singh D, Kraft M, Beghé B, Joubert P, Bossé Y, Sin D, Cordero AH, Timens W, Brandsma CA, Hao K, Nickle DC, Vonk JM, Nawijn MC, van den Berge M, Gosens R, Faiz A, Koppelman GH. El-Husseini ZW, et al. Among authors: timens w. Am J Respir Cell Mol Biol. 2025 Jan 21. doi: 10.1165/rcmb.2024-0251MA. Online ahead of print. Am J Respir Cell Mol Biol. 2025. PMID: 39836087
Molecular Tumor Board of the University Medical Center Groningen (UMCG-MTB): outcome of patients with rare or complex mutational profiles receiving MTB-advised targeted therapy.
de Jager VD, Plomp P, Paats MS, van Helvert S, Elst AT, van den Berg A, Dubbink HJ, van Geffen WH, Zhang L, Hendriks LEL, Hiltermann TJN, Hiddinga BI, Hijmering-Kappelle LBM, Jalving M, Kluiver J, Koopman B, van Kruchten M, van der Logt EMJ, Piet B, van Putten J, Reitsma BH, Rutgers SR, de Vries M, Stigt JA, Groves MR, Timens W, Willems SM, van Kempen LC, Schuuring E, van der Wekken AJ. de Jager VD, et al. Among authors: timens w. ESMO Open. 2024 Nov;9(11):103966. doi: 10.1016/j.esmoop.2024.103966. Epub 2024 Nov 4. ESMO Open. 2024. PMID: 39500140 Free PMC article.
Multi-ancestry GWAS meta-analyses of lung cancer reveal susceptibility loci and elucidate smoking-independent genetic risk.
Gorman BR, Ji SG, Francis M, Sendamarai AK, Shi Y, Devineni P, Saxena U, Partan E, DeVito AK, Byun J, Han Y, Xiao X, Sin DD, Timens W, Moser J, Muralidhar S, Ramoni R, Hung RJ, McKay JD, Bossé Y, Sun R, Amos CI; VA Million Veteran Program; Pyarajan S. Gorman BR, et al. Among authors: timens w. Nat Commun. 2024 Oct 4;15(1):8629. doi: 10.1038/s41467-024-52129-4. Nat Commun. 2024. PMID: 39366959 Free PMC article.
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