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IRF2 loss is associated with reduced MHC I pathway transcripts in subsets of most human cancers and causes resistance to checkpoint immunotherapy in human and mouse melanomas.
Sari G, Dhatchinamoorthy K, Orellano-Ariza L, Ferreira LM, Brehm MA, Rock K. Sari G, et al. Among authors: dhatchinamoorthy k. Res Sq [Preprint]. 2024 Sep 2:rs.3.rs-4997954. doi: 10.21203/rs.3.rs-4997954/v1. Res Sq. 2024. Update in: J Exp Clin Cancer Res. 2024 Oct 2;43(1):276. doi: 10.1186/s13046-024-03187-5 PMID: 39281881 Free PMC article. Updated. Preprint.
Regulation of kinetochore configuration during mitosis.
Dhatchinamoorthy K, Mattingly M, Gerton JL. Dhatchinamoorthy K, et al. Curr Genet. 2018 Dec;64(6):1197-1203. doi: 10.1007/s00294-018-0841-9. Epub 2018 Apr 27. Curr Genet. 2018. PMID: 29704052 Review.
Structural plasticity of the living kinetochore.
Dhatchinamoorthy K, Shivaraju M, Lange JJ, Rubinstein B, Unruh JR, Slaughter BD, Gerton JL. Dhatchinamoorthy K, et al. J Cell Biol. 2017 Nov 6;216(11):3551-3570. doi: 10.1083/jcb.201703152. Epub 2017 Sep 22. J Cell Biol. 2017. PMID: 28939613 Free PMC article.