MacDonald PE - Search Results

1

HumanIslets.com: Improving accessibility, integration, and usability of human research islet data.

Ewald JD, Lu Y, Ellis CE, Worton J, Kolic J, Sasaki S, Zhang D, Dos Santos T, Spigelman AF, Bautista A, Dai XQ, Lyon JG, Smith NP, Wong JM, Rajesh V, Sun H, Sharp SA, Rogalski JC, Moravcova R, Cen HH, Manning Fox JE; HumanIslets.com Consortium; Atlas E, Bruin JE, Mulvihill EE, Verchere CB, Foster LJ, Gloyn AL, Johnson JD, Pepper AR, Lynn FC, Xia J, MacDonald PE. Ewald JD, et al. Among authors: macdonald pe. Cell Metab. 2025 Jan 7;37(1):7-11. doi: 10.1016/j.cmet.2024.09.001. Epub 2024 Oct 1. Cell Metab. 2025. PMID: 39357523

2

SUMOylation regulates Kv2.1 and modulates pancreatic beta-cell excitability.

Dai XQ, Kolic J, Marchi P, Sipione S, Macdonald PE. Dai XQ, et al. Among authors: macdonald pe. J Cell Sci. 2009 Mar 15;122(Pt 6):775-9. doi: 10.1242/jcs.036632. Epub 2009 Feb 17. J Cell Sci. 2009. PMID: 19223394

3

Insulin granule recruitment and exocytosis is dependent on p110gamma in insulinoma and human beta-cells.

Pigeau GM, Kolic J, Ball BJ, Hoppa MB, Wang YW, Rückle T, Woo M, Manning Fox JE, MacDonald PE. Pigeau GM, et al. Among authors: macdonald pe. Diabetes. 2009 Sep;58(9):2084-92. doi: 10.2337/db08-1371. Epub 2009 Jun 23. Diabetes. 2009. PMID: 19549714 Free PMC article.

4

Inhibition of beta-cell sodium-calcium exchange enhances glucose-dependent elevations in cytoplasmic calcium and insulin secretion.

Hamming KS, Soliman D, Webster NJ, Searle GJ, Matemisz LC, Liknes DA, Dai XQ, Pulinilkunnil T, Riedel MJ, Dyck JR, Macdonald PE, Light PE. Hamming KS, et al. Among authors: macdonald pe. Diabetes. 2010 Jul;59(7):1686-93. doi: 10.2337/db09-0630. Epub 2010 Apr 22. Diabetes. 2010. PMID: 20413506 Free PMC article.

5

Voltage-dependent K(+) channels are positive regulators of alpha cell action potential generation and glucagon secretion in mice and humans.

Spigelman AF, Dai X, MacDonald PE. Spigelman AF, et al. Among authors: macdonald pe. Diabetologia. 2010 Sep;53(9):1917-26. doi: 10.1007/s00125-010-1759-z. Epub 2010 May 6. Diabetologia. 2010. PMID: 20446079

6

SUMOylation regulates insulin exocytosis downstream of secretory granule docking in rodents and humans.

Dai XQ, Plummer G, Casimir M, Kang Y, Hajmrle C, Gaisano HY, Manning Fox JE, MacDonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetes. 2011 Mar;60(3):838-47. doi: 10.2337/db10-0440. Epub 2011 Jan 24. Diabetes. 2011. PMID: 21266332 Free PMC article.

7

Islet cholesterol accumulation due to loss of ABCA1 leads to impaired exocytosis of insulin granules.

Kruit JK, Wijesekara N, Fox JE, Dai XQ, Brunham LR, Searle GJ, Morgan GP, Costin AJ, Tang R, Bhattacharjee A, Johnson JD, Light PE, Marsh BJ, Macdonald PE, Verchere CB, Hayden MR. Kruit JK, et al. Among authors: macdonald pe. Diabetes. 2011 Dec;60(12):3186-96. doi: 10.2337/db11-0081. Epub 2011 Oct 12. Diabetes. 2011. PMID: 21998401 Free PMC article.

8

The voltage-dependent potassium channel subunit Kv2.1 regulates insulin secretion from rodent and human islets independently of its electrical function.

Dai XQ, Manning Fox JE, Chikvashvili D, Casimir M, Plummer G, Hajmrle C, Spigelman AF, Kin T, Singer-Lahat D, Kang Y, Shapiro AM, Gaisano HY, Lotan I, Macdonald PE. Dai XQ, et al. Among authors: macdonald pe. Diabetologia. 2012 Jun;55(6):1709-20. doi: 10.1007/s00125-012-2512-6. Epub 2012 Mar 13. Diabetologia. 2012. PMID: 22411134

9

Novel roles of SUMO in pancreatic β-cells: thinking outside the nucleus.

Manning Fox JE, Hajmrle C, Macdonald PE. Manning Fox JE, et al. Among authors: macdonald pe. Can J Physiol Pharmacol. 2012 Jun;90(6):765-70. doi: 10.1139/y11-134. Epub 2012 Apr 9. Can J Physiol Pharmacol. 2012. PMID: 22486776 Review.

10

SSTR2 is the functionally dominant somatostatin receptor in human pancreatic β- and α-cells.

Kailey B, van de Bunt M, Cheley S, Johnson PR, MacDonald PE, Gloyn AL, Rorsman P, Braun M. Kailey B, et al. Among authors: macdonald pe. Am J Physiol Endocrinol Metab. 2012 Nov 1;303(9):E1107-16. doi: 10.1152/ajpendo.00207.2012. Epub 2012 Aug 28. Am J Physiol Endocrinol Metab. 2012. PMID: 22932785 Free PMC article.

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