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A novel peptide-based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies.
Aggidis A, Devitt G, Zhang Y, Chatterjee S, Townsend D, Fullwood NJ, Ortega ER, Tarutani A, Hasegawa M, Cooper A, Williamson P, Mendoza-Oliva A, Diamond MI, Mudher A, Allsop D. Aggidis A, et al. Among authors: diamond mi. Alzheimers Dement. 2024 Nov;20(11):7788-7804. doi: 10.1002/alz.14246. Epub 2024 Oct 3. Alzheimers Dement. 2024. PMID: 39360630 Free PMC article.
RNA induces unique tau strains and stabilizes Alzheimer's disease seeds.
Zwierzchowski-Zarate AN, Mendoza-Oliva A, Kashmer OM, Collazo-Lopez JE, White CL 3rd, Diamond MI. Zwierzchowski-Zarate AN, et al. Among authors: diamond mi. J Biol Chem. 2022 Aug;298(8):102132. doi: 10.1016/j.jbc.2022.102132. Epub 2022 Jun 11. J Biol Chem. 2022. PMID: 35700826 Free PMC article.
DnaJC7 specifically regulates tau seeding.
Perez VA, Sanders DW, Mendoza-Oliva A, Stopschinski BE, Mullapudi V, White CL, Joachimiak LA, Diamond MI. Perez VA, et al. Among authors: diamond mi. Elife. 2023 Jun 30;12:e86936. doi: 10.7554/eLife.86936. Elife. 2023. PMID: 37387473 Free PMC article.
Tau strains shape disease.
Vaquer-Alicea J, Diamond MI, Joachimiak LA. Vaquer-Alicea J, et al. Among authors: diamond mi. Acta Neuropathol. 2021 Jul;142(1):57-71. doi: 10.1007/s00401-021-02301-7. Epub 2021 Apr 8. Acta Neuropathol. 2021. PMID: 33830330 Free PMC article. Review.
110 results