Hasegawa M - Search Results

1

A novel peptide-based tau aggregation inhibitor as a potential therapeutic for Alzheimer's disease and other tauopathies.

Aggidis A, Devitt G, Zhang Y, Chatterjee S, Townsend D, Fullwood NJ, Ortega ER, Tarutani A, Hasegawa M, Cooper A, Williamson P, Mendoza-Oliva A, Diamond MI, Mudher A, Allsop D. Aggidis A, et al. Among authors: hasegawa m. Alzheimers Dement. 2024 Nov;20(11):7788-7804. doi: 10.1002/alz.14246. Epub 2024 Oct 3. Alzheimers Dement. 2024. PMID: 39360630 Free PMC article.

2

[Role of Structural Polymorphisms of Tau Filaments in the Pathological Diversity of Tauopathies].

Tarutani A, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. Brain Nerve. 2022 Jul;74(7):919-925. doi: 10.11477/mf.1416202150. Brain Nerve. 2022. PMID: 35860941 Review. Japanese.

3

[The Prion-like Mechanism in Neurodegenerative Diseases-Current Studies and Future Prospects].

Tarutani A, Hisanaga SI, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. Brain Nerve. 2016 Oct;68(10):1197-1204. doi: 10.11477/mf.1416200573. Brain Nerve. 2016. PMID: 27703107 Review. Japanese.

4

Prion-like propagation of α-synuclein in neurodegenerative diseases.

Tarutani A, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. Prog Mol Biol Transl Sci. 2019;168:323-348. doi: 10.1016/bs.pmbts.2019.07.005. Epub 2019 Jul 31. Prog Mol Biol Transl Sci. 2019. PMID: 31699325 Review.

5

Ultrastructures of α-Synuclein Filaments in Synucleinopathy Brains and Experimental Models.

Tarutani A, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. J Mov Disord. 2024 Jan;17(1):15-29. doi: 10.14802/jmd.23213. Epub 2023 Nov 22. J Mov Disord. 2024. PMID: 37990381 Free PMC article.

6

Electron Microscopic Analysis of α-Synuclein Fibrils.

Tarutani A, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. Methods Mol Biol. 2021;2322:17-25. doi: 10.1007/978-1-0716-1495-2_2. Methods Mol Biol. 2021. PMID: 34043188

7

Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods.

Tarutani A, Arai T, Murayama S, Hisanaga SI, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. Acta Neuropathol Commun. 2018 Apr 18;6(1):29. doi: 10.1186/s40478-018-0532-2. Acta Neuropathol Commun. 2018. PMID: 29669601 Free PMC article.

8

The Effect of Fragmented Pathogenic α-Synuclein Seeds on Prion-like Propagation.

Tarutani A, Suzuki G, Shimozawa A, Nonaka T, Akiyama H, Hisanaga S, Hasegawa M. Tarutani A, et al. Among authors: hasegawa m. J Biol Chem. 2016 Sep 2;291(36):18675-88. doi: 10.1074/jbc.M116.734707. Epub 2016 Jul 5. J Biol Chem. 2016. PMID: 27382062 Free PMC article.

9

Novel tau filament fold in corticobasal degeneration.

Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Zhang W, et al. Among authors: hasegawa m. Nature. 2020 Apr;580(7802):283-287. doi: 10.1038/s41586-020-2043-0. Epub 2020 Feb 12. Nature. 2020. PMID: 32050258 Free PMC article.

10

Human tauopathy-derived tau strains determine the substrates recruited for templated amplification.

Tarutani A, Miyata H, Nonaka T, Hasegawa K, Yoshida M, Saito Y, Murayama S, Robinson AC, Mann DMA, Tomita T, Hasegawa M. Tarutani A, et al. Among authors: hasegawa k, hasegawa m. Brain. 2021 Sep 4;144(8):2333-2348. doi: 10.1093/brain/awab091. Brain. 2021. PMID: 33693528 Free PMC article.

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