Aoyama M - Search Results

1

Linker and Conjugation Site Synergy in Antibody-Drug Conjugates: Impacts on Biological Activity.

Aoyama M, Tada M, Yokoo H, Ito T, Misawa T, Demizu Y, Ishii-Watabe A. Aoyama M, et al. Bioconjug Chem. 2024 Oct 3;35(10):1568-76. doi: 10.1021/acs.bioconjchem.4c00348. Online ahead of print. Bioconjug Chem. 2024. PMID: 39363433

2

Effects of amino acid substitutions on the biological activity of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori).

Aoyama M, Tada M, Tatematsu KI, Hashii N, Sezutsu H, Ishii-Watabe A. Aoyama M, et al. Biochem Biophys Res Commun. 2018 Sep 18;503(4):2633-2638. doi: 10.1016/j.bbrc.2018.08.015. Epub 2018 Aug 14. Biochem Biophys Res Commun. 2018. PMID: 30119885

3

A Cell-Based Reporter Assay Measuring the Activation of Fc Gamma Receptors Induced by Therapeutic Monoclonal Antibodies.

Aoyama M, Tada M, Ishii-Watabe A. Aoyama M, et al. Methods Mol Biol. 2019;1904:423-429. doi: 10.1007/978-1-4939-8958-4_21. Methods Mol Biol. 2019. PMID: 30539484

4

Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies.

Aoyama M, Hashii N, Tsukimura W, Osumi K, Harazono A, Tada M, Kiyoshi M, Matsuda A, Ishii-Watabe A. Aoyama M, et al. MAbs. 2019 Jul;11(5):826-836. doi: 10.1080/19420862.2019.1608143. Epub 2019 May 8. MAbs. 2019. PMID: 30990348 Free PMC article.

5

Fcγ Receptor Activation by Human Monoclonal Antibody Aggregates.

Tada M, Aoyama M, Ishii-Watabe A. Tada M, et al. Among authors: aoyama m. J Pharm Sci. 2020 Jan;109(1):576-583. doi: 10.1016/j.xphs.2019.10.046. Epub 2019 Oct 30. J Pharm Sci. 2020. PMID: 31676270 Free article.

6

Recent Achievements and Current Interests in Research on the Characterization and Quality Control of Biopharmaceuticals in Japan.

Ishii-Watabe A, Shibata H, Suetomo H, Ikeda Y, Telikepalli S, Kiyoshi M, Hayashi Y, Muto T, Tanaka Y, Ueda S, Iwura T, Saitoh S, Aoyama M, Harazono A, Hyuga M, Goda Y, Torisu T, Uchiyama S. Ishii-Watabe A, et al. Among authors: aoyama m. J Pharm Sci. 2020 May;109(5):1652-1661. doi: 10.1016/j.xphs.2020.01.001. Epub 2020 Jan 9. J Pharm Sci. 2020. PMID: 31927040

7

Characterization of Aggregated Antibody-Silicone Oil Complexes: From Perspectives of Morphology, 3D Image, and Fcγ Receptor Activation.

Kiyoshi M, Tada M, Shibata H, Aoyama M, Ishii-Watabe A. Kiyoshi M, et al. Among authors: aoyama m. J Pharm Sci. 2021 Mar;110(3):1189-1196. doi: 10.1016/j.xphs.2020.10.022. Epub 2020 Oct 15. J Pharm Sci. 2021. PMID: 33069712 Free article.

8

Fcγ Receptor-Dependent Internalization and Off-Target Cytotoxicity of Antibody-Drug Conjugate Aggregates.

Aoyama M, Tada M, Yokoo H, Demizu Y, Ishii-Watabe A. Aoyama M, et al. Pharm Res. 2022 Jan;39(1):89-103. doi: 10.1007/s11095-021-03158-x. Epub 2021 Dec 27. Pharm Res. 2022. PMID: 34961908 Free PMC article.

9

FcγRIIIa-158V/F polymorphism affects the performance of FcγRIIIa-related bioassay.

Aoyama M, Tada M, Ishii-Watabe A. Aoyama M, et al. Biochem Biophys Res Commun. 2022 Jun 11;608:149-155. doi: 10.1016/j.bbrc.2022.04.001. Epub 2022 Apr 5. Biochem Biophys Res Commun. 2022. PMID: 35398612

10

Characterization of anti-SARS-CoV-2 monoclonal antibodies focusing on antigen binding, neutralization, and FcγR activation via formation of immune complex.

Tada M, Aoyama M, Ishii-Watabe A. Tada M, et al. Among authors: aoyama m. MAbs. 2023 Jan-Dec;15(1):2222874. doi: 10.1080/19420862.2023.2222874. MAbs. 2023. PMID: 37309192 Free PMC article.

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