Misawa T - Search Results

1

Linker and Conjugation Site Synergy in Antibody-Drug Conjugates: Impacts on Biological Activity.

Aoyama M, Tada M, Yokoo H, Ito T, Misawa T, Demizu Y, Ishii-Watabe A. Aoyama M, et al. Among authors: misawa t. Bioconjug Chem. 2024 Oct 3;35(10):1568-76. doi: 10.1021/acs.bioconjchem.4c00348. Online ahead of print. Bioconjug Chem. 2024. PMID: 39363433

2

Development of cell-penetrating R7 fragment-conjugated helical peptides as inhibitors of estrogen receptor-mediated transcription.

Nagakubo T, Demizu Y, Kanda Y, Misawa T, Shoda T, Okuhira K, Sekino Y, Naito M, Kurihara M. Nagakubo T, et al. Among authors: misawa t. Bioconjug Chem. 2014 Nov 19;25(11):1921-4. doi: 10.1021/bc500480e. Epub 2014 Nov 7. Bioconjug Chem. 2014. PMID: 25375254

3

Structural development of stapled short helical peptides as vitamin D receptor (VDR)-coactivator interaction inhibitors.

Misawa T, Demizu Y, Kawamura M, Yamagata N, Kurihara M. Misawa T, et al. Bioorg Med Chem. 2015 Mar 1;23(5):1055-61. doi: 10.1016/j.bmc.2015.01.007. Epub 2015 Jan 12. Bioorg Med Chem. 2015. PMID: 25637122

4

Effects of D-Leu residues on the helical secondary structures of L-Leu-based nonapeptides.

Demizu Y, Yamashita H, Misawa T, Doi M, Tanaka M, Kurihara M. Demizu Y, et al. Among authors: misawa t. Chem Pharm Bull (Tokyo). 2015;63(3):218-24. doi: 10.1248/cpb.c14-00760. Chem Pharm Bull (Tokyo). 2015. PMID: 25757493 Free article.

5

A preorganized β-amino acid bearing a guanidinium side chain and its use in cell-penetrating peptides.

Demizu Y, Oba M, Okitsu K, Yamashita H, Misawa T, Tanaka M, Kurihara M, Gellman SH. Demizu Y, et al. Among authors: misawa t. Org Biomol Chem. 2015 May 28;13(20):5617-20. doi: 10.1039/c5ob00389j. Epub 2015 Apr 21. Org Biomol Chem. 2015. PMID: 25897867

6

Design, synthesis, and anti-HIV-1 activity of 1-aromatic methyl-substituted 3-(3,5-dimethylbenzyl)uracil and N-3,5-dimethylbenzyl-substituted urea derivatives.

Sakakibara N, Baba M, Okamoto M, Toyama M, Demizu Y, Misawa T, Kurihara M, Irie K, Kato Y, Maruyama T. Sakakibara N, et al. Among authors: misawa t. Antivir Chem Chemother. 2015 Feb;24(1):3-18. doi: 10.1177/2040206614566584. Antivir Chem Chemother. 2015. PMID: 26149262 Free PMC article.

7

Structural development of stabilized helical peptides as inhibitors of estrogen receptor (ER)-mediated transcription.

Demizu Y, Misawa T, Nagakubo T, Kanda Y, Okuhira K, Sekino Y, Naito M, Kurihara M. Demizu Y, et al. Among authors: misawa t. Bioorg Med Chem. 2015 Aug 1;23(15):4132-4138. doi: 10.1016/j.bmc.2015.06.067. Epub 2015 Jul 2. Bioorg Med Chem. 2015. PMID: 26183544

8

Topological Study of the Structures of Heterochiral Peptides Containing Equal Amounts of l-Leu and d-Leu.

Demizu Y, Yamashita H, Doi M, Misawa T, Oba M, Tanaka M, Kurihara M. Demizu Y, et al. Among authors: misawa t. J Org Chem. 2015 Sep 4;80(17):8597-603. doi: 10.1021/acs.joc.5b01541. Epub 2015 Aug 22. J Org Chem. 2015. PMID: 26274390

9

Effects of alkyl side chains and terminal hydrophilicity on vitamin D receptor (VDR) agonistic activity based on the diphenylpentane skeleton.

Misawa T, Yorioka M, Demizu Y, Noguchi-Yachide T, Ohoka N, Kurashima-Kinoshita M, Motoyoshi H, Nojiri H, Kittaka A, Makishima M, Naito M, Kurihara M. Misawa T, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5362-6. doi: 10.1016/j.bmcl.2015.09.030. Epub 2015 Sep 12. Bioorg Med Chem Lett. 2015. PMID: 26432035

10

Design, synthesis, and anti-HIV-1 activity of 1-substituted 3-(3,5-dimethylbenzyl)triazine derivatives.

Sakakibara N, Balboni G, Congiu C, Onnis V, Demizu Y, Misawa T, Kurihara M, Kato Y, Maruyama T, Toyama M, Okamoto M, Baba M. Sakakibara N, et al. Among authors: misawa t. Antivir Chem Chemother. 2015 Apr;24(2):62-71. doi: 10.1177/2040206615612208. Epub 2015 Oct 28. Antivir Chem Chemother. 2015. PMID: 26514833 Free PMC article.

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