Upreti VV - Search Results

1

Oncology Combination Drug Development Strategies for Project Optimus.

Yap TA, Bullock J, Chong S, Doyle MK, Hussain A, Kline J, Manon A, Venkatakrishnan K, Upreti VV. Yap TA, et al. Among authors: upreti vv. Clin Cancer Res. 2024 Dec 2;30(23):5237-5241. doi: 10.1158/1078-0432.CCR-24-1836. Clin Cancer Res. 2024. PMID: 39365679 Review.

2

Model-Based Meta-Analysis: Optimizing Research, Development, and Utilization of Therapeutics Using the Totality of Evidence.

Upreti VV, Venkatakrishnan K. Upreti VV, et al. Clin Pharmacol Ther. 2019 Nov;106(5):981-992. doi: 10.1002/cpt.1462. Epub 2019 Jun 14. Clin Pharmacol Ther. 2019. PMID: 30993679 Review.

3

Dose Optimization in Oncology Drug Development: An International Consortium for Innovation and Quality in Pharmaceutical Development White Paper.

Samineni D, Venkatakrishnan K, Othman AA, Pithavala YK, Poondru S, Patel C, Vaddady P, Ankrom W, Ramanujan S, Budha N, Wu M, Haddish-Berhane N, Fritsch H, Hussain A, Kanodia J, Li M, Li M, Melhem M, Parikh A, Upreti VV, Gupta N. Samineni D, et al. Among authors: upreti vv. Clin Pharmacol Ther. 2024 Sep;116(3):531-545. doi: 10.1002/cpt.3298. Epub 2024 May 16. Clin Pharmacol Ther. 2024. PMID: 38752712 Review.

4

Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC).

Zhou D, Byers LA, Sable B, Smit MD, Sadraei NH, Dutta S, Upreti VV. Zhou D, et al. Among authors: upreti vv. J Clin Pharmacol. 2024 Mar;64(3):362-370. doi: 10.1002/jcph.2346. Epub 2023 Oct 2. J Clin Pharmacol. 2024. PMID: 37694295

5

Predicting Clinical Pharmacokinetics/Pharmacodynamics and Impact of Organ Impairment on siRNA-Based Therapeutics Using a Mechanistic Physiologically-Based Pharmacokinetic-Pharmacodynamic Model.

Lumen A, Zhang X, Dutta S, Upreti VV. Lumen A, et al. Among authors: upreti vv. Clin Pharmacol Ther. 2024 May;115(5):1054-1064. doi: 10.1002/cpt.3160. Epub 2024 Jan 28. Clin Pharmacol Ther. 2024. PMID: 38282246

6

Recent advances and clinical pharmacology aspects of Chimeric Antigen Receptor (CAR) T-cellular therapy development.

Kast J, Nozohouri S, Zhou D, Yago MR, Chen PW, Ahamadi M, Dutta S, Upreti VV. Kast J, et al. Among authors: upreti vv. Clin Transl Sci. 2022 Sep;15(9):2057-2074. doi: 10.1111/cts.13349. Epub 2022 Jul 2. Clin Transl Sci. 2022. PMID: 35677992 Free PMC article. Review.

7

Meta-analysis of hepatic cytochrome P450 ontogeny to underwrite the prediction of pediatric pharmacokinetics using physiologically based pharmacokinetic modeling.

Upreti VV, Wahlstrom JL. Upreti VV, et al. J Clin Pharmacol. 2016 Mar;56(3):266-83. doi: 10.1002/jcph.585. Epub 2015 Oct 9. J Clin Pharmacol. 2016. PMID: 26139104

8

Risk-Based Pharmacokinetic and Drug-Drug Interaction Characterization of Antibody-Drug Conjugates in Oncology Clinical Development: An International Consortium for Innovation and Quality in Pharmaceutical Development Perspective.

Li C, Menon R, Walles M, Singh R, Upreti VV, Brackman D, Lee AJ, Endres CJ, Kumar S, Zhang D, Barletta F, Suri A, Hainzl D, Liao KH, Lalovic B, Beaumont M, Zuo P, Mayer AP, Wei D. Li C, et al. Among authors: upreti vv. Clin Pharmacol Ther. 2022 Oct;112(4):754-769. doi: 10.1002/cpt.2448. Epub 2021 Nov 23. Clin Pharmacol Ther. 2022. PMID: 34657311

9

A Mechanistic Physiologically-Based Pharmacokinetic Platform Model to Guide Adult and Pediatric Intravenous and Subcutaneous Dosing for Bispecific T Cell Engagers.

Zhang X, Lumen A, Wong H, Connarn J, Dutta S, Upreti VV. Zhang X, et al. Among authors: upreti vv. Clin Pharmacol Ther. 2024 Mar;115(3):457-467. doi: 10.1002/cpt.3056. Epub 2023 Oct 11. Clin Pharmacol Ther. 2024. PMID: 37746860

10

Panitumumab: A Review of Clinical Pharmacokinetic and Pharmacology Properties After Over a Decade of Experience in Patients with Solid Tumors.

Kast J, Dutta S, Upreti VV. Kast J, et al. Among authors: upreti vv. Adv Ther. 2021 Jul;38(7):3712-3723. doi: 10.1007/s12325-021-01809-4. Epub 2021 Jun 18. Adv Ther. 2021. PMID: 34152568 Review.

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