SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor.
Alnouri MW, Roquid KA, Bonnavion R, Cho H, Heering J, Kwon J, Jäger Y, Wang S, Günther S, Wettschureck N, Geisslinger G, Gurke R, Müller CE, Proschak E, Offermanns S.
Alnouri MW, et al. Among authors: gurke r.
Proc Natl Acad Sci U S A. 2024 Oct 8;121(41):e2407130121. doi: 10.1073/pnas.2407130121. Epub 2024 Oct 4.
Proc Natl Acad Sci U S A. 2024.
PMID: 39365815
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