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The common, VTE-protective, G haplotype of F5 increases factor V-short, TFPI function, and risk of bleeding.
Sims MC, Gierula M, Stephens JC, Tokolyi A, Stefanucci L, Persyn E, Sun L, Collins JH, Davenport E, Di Angelantonio E, Downes K, Inouye M, Paul DS, Thomas W, Tolios A, BioResource N, Ouwehand WH, Gleadall NS, Crawley JTB, Butterworth AS, Frontini M, Ahnstrom J. Sims MC, et al. Among authors: tolios a. Blood Adv. 2024 Oct 4:bloodadvances.2024014020. doi: 10.1182/bloodadvances.2024014020. Online ahead of print. Blood Adv. 2024. PMID: 39365993
Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders.
Downes K, Megy K, Duarte D, Vries M, Gebhart J, Hofer S, Shamardina O, Deevi SVV, Stephens J, Mapeta R, Tuna S, Al Hasso N, Besser MW, Cooper N, Daugherty L, Gleadall N, Greene D, Haimel M, Martin H, Papadia S, Revel-Vilk S, Sivapalaratnam S, Symington E, Thomas W, Thys C, Tolios A, Penkett CJ; NIHR BioResource; Ouwehand WH, Abbs S, Laffan MA, Turro E, Simeoni I, Mumford AD, Henskens YMC, Pabinger I, Gomez K, Freson K. Downes K, et al. Among authors: tolios a. Blood. 2019 Dec 5;134(23):2082-2091. doi: 10.1182/blood.2018891192. Blood. 2019. PMID: 31064749 Free PMC article.
Thrombomodulin in patients with mild to moderate bleeding tendency.
Mehic D, Tolios A, Hofer S, Ay C, Haslacher H, Downes K, Haimel M, Pabinger I, Gebhart J. Mehic D, et al. Among authors: tolios a. Haemophilia. 2021 Nov;27(6):1028-1036. doi: 10.1111/hae.14433. Epub 2021 Oct 10. Haemophilia. 2021. PMID: 34628704 Free PMC article.
A comprehensive survey of artificial intelligence adoption in European laboratory medicine: current utilization and prospects.
Cadamuro J, Carobene A, Cabitza F, Debeljak Z, De Bruyne S, van Doorn W, Johannes E, Frans G, Özdemir H, Martin Perez S, Rajdl D, Tolios A, Padoan A; European Federation of Clinical Chemistry and Laboratory Medicine Working Group on Artificial Intelligence. Cadamuro J, et al. Among authors: tolios a. Clin Chem Lab Med. 2024 Oct 24. doi: 10.1515/cclm-2024-1016. Online ahead of print. Clin Chem Lab Med. 2024. PMID: 39443973 Free article.
A novel EGFR inhibitor acts as potent tool for hypoxia-activated prodrug systems and exerts strong synergistic activity with VEGFR inhibition in vitro and in vivo.
Caban M, Koblmueller B, Groza D, Schueffl HH, Terenzi A, Tolios A, Mohr T, Mathuber M, Kryeziu K, Jaunecker C, Pirker C, Keppler BK, Berger W, Kowol CR, Heffeter P. Caban M, et al. Among authors: tolios a. Cancer Lett. 2023 Jul 1;565:216237. doi: 10.1016/j.canlet.2023.216237. Epub 2023 May 19. Cancer Lett. 2023. PMID: 37211067 Free article.
Potentials and pitfalls of ChatGPT and natural-language artificial intelligence models for the understanding of laboratory medicine test results. An assessment by the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) Working Group on Artificial Intelligence (WG-AI).
Cadamuro J, Cabitza F, Debeljak Z, De Bruyne S, Frans G, Perez SM, Ozdemir H, Tolios A, Carobene A, Padoan A. Cadamuro J, et al. Among authors: tolios a. Clin Chem Lab Med. 2023 Apr 24;61(7):1158-1166. doi: 10.1515/cclm-2023-0355. Print 2023 Jun 27. Clin Chem Lab Med. 2023. PMID: 37083166 Free article.
31 results