Hadden MK - Search Results

1

Probing hot spots of protein-protein interactions mediated by the safety-belt region of REV7.

Dash RC, Arianna GA, Patel SM, Rizzo AA, Harrahill NJ, Korzhnev DM, Hadden MK. Dash RC, et al. Among authors: hadden mk. Structure. 2024 Nov 7;32(11):2134-2146.e3. doi: 10.1016/j.str.2024.09.007. Epub 2024 Oct 3. Structure. 2024. PMID: 39366370

2

Development of Enterovirus Antiviral Agents That Target the Viral 2C Protein.

Kejriwal R, Evans T, Calabrese J, Swistak L, Alexandrescu L, Cohen M, Rahman N, Henriksen N, Charan Dash R, Hadden MK, Stonehouse NJ, Rowlands DJ, Kingston NJ, Hartnoll M, Dobson SJ, White SJ. Kejriwal R, et al. Among authors: hadden mk. ChemMedChem. 2023 May 16;18(10):e202200541. doi: 10.1002/cmdc.202200541. Epub 2023 Mar 10. ChemMedChem. 2023. PMID: 36792530

3

Discovery of small molecules against porcine reproductive and respiratory syndrome virus replication by targeting NendoU activity.

Zhu J, Lai Y, Cheng M, Dash RC, Guo S, Guo J, Su Y, Wolek A, Issacs B, Liu Z, Li Q, Mishra N, Garmendia A, Hadden MK, Tian XC, He X, Tang Y. Zhu J, et al. Among authors: hadden mk. J Virol. 2024 Dec 31:e0203424. doi: 10.1128/jvi.02034-24. Online ahead of print. J Virol. 2024. PMID: 39745451 Free article.

4

Small molecules that regulate the N⁶-methyladenosine RNA modification as potential anti-cancer agents.

Harrahill NJ, Hadden MK. Harrahill NJ, et al. Among authors: hadden mk. Eur J Med Chem. 2024 Aug 5;274:116526. doi: 10.1016/j.ejmech.2024.116526. Epub 2024 May 22. Eur J Med Chem. 2024. PMID: 38805939 Review.

5

Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction.

Zaino AM, Dash RC, James SJ, MacGilvary N, Crompton A, McPherson KS, Stanzione M, Korzhnev DM, Dyson NJ, Chatterjee N, Cantor SB, Hadden MK. Zaino AM, et al. Among authors: hadden mk. Bioorg Med Chem. 2024 May 15;106:117755. doi: 10.1016/j.bmc.2024.117755. Epub 2024 May 9. Bioorg Med Chem. 2024. PMID: 38749343

6

DNA Sequence Specificity Reveals a Role of the HLTF HIRAN Domain in the Recognition of Trinucleotide Repeats.

Dusek CO, Dash RC, McPherson KS, Calhoun JT, Bezsonova I, Korzhnev DM, Hadden MK. Dusek CO, et al. Among authors: hadden mk. Biochemistry. 2022 May 24:10.1021/acs.biochem.2c00027. doi: 10.1021/acs.biochem.2c00027. Online ahead of print. Biochemistry. 2022. PMID: 35608245 Free PMC article.

7

Translesion DNA synthesis mediates acquired resistance to olaparib plus temozolomide in small cell lung cancer.

Stanzione M, Zhong J, Wong E, LaSalle TJ, Wise JF, Simoneau A, Myers DT, Phat S, Sade-Feldman M, Lawrence MS, Hadden MK, Zou L, Farago AF, Dyson NJ, Drapkin BJ. Stanzione M, et al. Among authors: hadden mk. Sci Adv. 2022 May 13;8(19):eabn1229. doi: 10.1126/sciadv.abn1229. Epub 2022 May 13. Sci Adv. 2022. PMID: 35559669 Free PMC article.

8

Affinity-based protein profiling identifies vitamin D3 as a heat shock protein 70 antagonist that regulates hedgehog transduction in murine basal cell carcinoma.

Wen J, Hadden MK. Wen J, et al. Among authors: hadden mk. Eur J Med Chem. 2022 Jan 15;228:114005. doi: 10.1016/j.ejmech.2021.114005. Epub 2021 Nov 20. Eur J Med Chem. 2022. PMID: 34844141

9

REV1 Inhibition Enhances Radioresistance and Autophagy.

Ikeh KE, Lamkin EN, Crompton A, Deutsch J, Fisher KJ, Gray M, Argyle DJ, Lim WY, Korzhnev DM, Hadden MK, Hong J, Zhou P, Chatterjee N. Ikeh KE, et al. Among authors: hadden mk. Cancers (Basel). 2021 Oct 21;13(21):5290. doi: 10.3390/cancers13215290. Cancers (Basel). 2021. PMID: 34771454 Free PMC article.

10

A platform utilizing Drosophila ovulation for nonhormonal contraceptive screening.

Jiang K, Zhang J, Huang Y, Wang Y, Xiao S, Hadden MK, Woodruff TK, Sun J. Jiang K, et al. Among authors: hadden mk. Proc Natl Acad Sci U S A. 2021 Jul 13;118(28):e2026403118. doi: 10.1073/pnas.2026403118. Proc Natl Acad Sci U S A. 2021. PMID: 34260376 Free PMC article.

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