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[3H]Dopamine Uptake through the Dopamine and Norepinephrine Transporters is Decreased in the Prefrontal Cortex of Transgenic Mice Expressing HIV-1 Transactivator of Transcription Protein.
Strauss M, O'Donovan B, Ma Y, Xiao Z, Lin S, Bardo MT, Ortinski PI, McLaughlin JP, Zhu J. Strauss M, et al. Among authors: zhu j. J Pharmacol Exp Ther. 2020 Aug;374(2):241-251. doi: 10.1124/jpet.120.266023. Epub 2020 May 27. J Pharmacol Exp Ther. 2020. PMID: 32461322 Free PMC article.
Substance abuse and neurotransmission.
Davis S, Zhu J. Davis S, et al. Among authors: zhu j. Adv Pharmacol. 2022;93:403-441. doi: 10.1016/bs.apha.2021.10.007. Epub 2022 Jan 17. Adv Pharmacol. 2022. PMID: 35341573 Free PMC article.
SRI-32743, a novel allosteric modulator, attenuates HIV-1 Tat protein-induced inhibition of the dopamine transporter and alleviates the potentiation of cocaine reward in HIV-1 Tat transgenic mice.
Zhu J, Quizon PM, Wang Y, Adeniran CA, Strauss MJ, Jiménez-Torres AC, Patel P, Cirino TJ, Eans SO, Hammond HR, Deliscar LS, O'Hara P, Saini SK, Ofori E, Vekariya RH, Zhang S, Moukha-Chafiq O, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhan CG, McLaughlin JP. Zhu J, et al. Neuropharmacology. 2022 Dec 1;220:109239. doi: 10.1016/j.neuropharm.2022.109239. Epub 2022 Sep 17. Neuropharmacology. 2022. PMID: 36126727
Novel Allosteric Modulator Southern Research Institute-32743 Reverses HIV-1 Transactivator of Transcription-Induced Increase in Dopamine Release in the Caudate Putamen of Inducible Transactivator of Transcription Transgenic Mice.
Davis SE, Ferris MJ, Ananthan S, Augelli-Szafran CE, Zhu J. Davis SE, et al. Among authors: zhu j. J Pharmacol Exp Ther. 2023 Feb;384(2):306-314. doi: 10.1124/jpet.122.001291. Epub 2022 Dec 1. J Pharmacol Exp Ther. 2023. PMID: 36456195 Free PMC article.
Identification of pyrimidine structure-based compounds as allosteric ligands of the dopamine transporter as therapeutic agents for NeuroHIV.
Jimenez-Torres AC, Hastie JA, Davis SE, Porter KD, Lei B, Moukha-Chafiq O, Zhang S, Nguyen TH, Ananthan S, Augelli-Szafran CE, Zhu J. Jimenez-Torres AC, et al. Among authors: zhu j. J Pharmacol Exp Ther. 2024 Sep 16:JPET-AR-2024-002138. doi: 10.1124/jpet.124.002138. Online ahead of print. J Pharmacol Exp Ther. 2024. PMID: 39284625 Free article.
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