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11C-UCB-J PET imaging is consistent with lower synaptic density in autistic adults.
Matuskey D, Yang Y, Naganawa M, Koohsari S, Toyonaga T, Gravel P, Pittman B, Torres K, Pisani L, Finn C, Cramer-Benjamin S, Herman N, Rosenthal LH, Franke CJ, Walicki BM, Esterlis I, Skosnik P, Radhakrishnan R, Wolf JM, Nabulsi N, Ropchan J, Huang Y, Carson RE, Naples AJ, McPartland JC. Matuskey D, et al. Among authors: carson re. Mol Psychiatry. 2024 Oct 4. doi: 10.1038/s41380-024-02776-2. Online ahead of print. Mol Psychiatry. 2024. PMID: 39367053
In vivo evidence of lower synaptic vesicle density in schizophrenia.
Radhakrishnan R, Skosnik PD, Ranganathan M, Naganawa M, Toyonaga T, Finnema S, Hillmer AT, Esterlis I, Huang Y, Nabulsi N, Carson RE, D'Souza DC. Radhakrishnan R, et al. Among authors: carson re. Mol Psychiatry. 2021 Dec;26(12):7690-7698. doi: 10.1038/s41380-021-01184-0. Epub 2021 Jun 16. Mol Psychiatry. 2021. PMID: 34135473
Imaging the effect of ketamine on synaptic density (SV2A) in the living brain.
Holmes SE, Finnema SJ, Naganawa M, DellaGioia N, Holden D, Fowles K, Davis M, Ropchan J, Emory P, Ye Y, Nabulsi N, Matuskey D, Angarita GA, Pietrzak RH, Duman RS, Sanacora G, Krystal JH, Carson RE, Esterlis I. Holmes SE, et al. Among authors: carson re. Mol Psychiatry. 2022 Apr;27(4):2273-2281. doi: 10.1038/s41380-022-01465-2. Epub 2022 Feb 15. Mol Psychiatry. 2022. PMID: 35165397 Free PMC article.
The regional pattern of age-related synaptic loss in the human brain differs from gray matter volume loss: in vivo PET measurement with [11C]UCB-J.
Toyonaga T, Khattar N, Wu Y, Lu Y, Naganawa M, Gallezot JD, Matuskey D, Mecca AP, Pittman B, Dias M, Nabulsi NB, Finnema SJ, Chen MK, Arnsten A, Radhakrishnan R, Skosnik PD, D'Souza DC, Esterlis I, Huang Y, van Dyck CH, Carson RE. Toyonaga T, et al. Among authors: carson re. Eur J Nucl Med Mol Imaging. 2024 Mar;51(4):1012-1022. doi: 10.1007/s00259-023-06487-8. Epub 2023 Nov 13. Eur J Nucl Med Mol Imaging. 2024. PMID: 37955791
Pancreatic beta cell mass PET imaging and quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in rodent models of diabetes.
Singhal T, Ding YS, Weinzimmer D, Normandin MD, Labaree D, Ropchan J, Nabulsi N, Lin SF, Skaddan MB, Soeller WC, Huang Y, Carson RE, Treadway JL, Cline GW. Singhal T, et al. Among authors: carson re. Mol Imaging Biol. 2011 Oct;13(5):973-84. doi: 10.1007/s11307-010-0406-x. Epub 2010 Sep 8. Mol Imaging Biol. 2011. PMID: 20824509 Free PMC article.
Imaging synaptic density in the living human brain.
Finnema SJ, Nabulsi NB, Eid T, Detyniecki K, Lin SF, Chen MK, Dhaher R, Matuskey D, Baum E, Holden D, Spencer DD, Mercier J, Hannestad J, Huang Y, Carson RE. Finnema SJ, et al. Among authors: carson re. Sci Transl Med. 2016 Jul 20;8(348):348ra96. doi: 10.1126/scitranslmed.aaf6667. Sci Transl Med. 2016. PMID: 27440727 Clinical Trial.
Ketamine-induced reduction in mGluR5 availability is associated with an antidepressant response: an [11C]ABP688 and PET imaging study in depression.
Esterlis I, DellaGioia N, Pietrzak RH, Matuskey D, Nabulsi N, Abdallah CG, Yang J, Pittenger C, Sanacora G, Krystal JH, Parsey RV, Carson RE, DeLorenzo C. Esterlis I, et al. Among authors: carson re. Mol Psychiatry. 2018 Apr;23(4):824-832. doi: 10.1038/mp.2017.58. Epub 2017 Apr 11. Mol Psychiatry. 2018. PMID: 28397841 Free PMC article.
631 results