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Discovery of a nasal spray steroid, tixocortol, as an inhibitor of SARS-CoV-2 main protease and viral replication.
Davis DA, Nair A, Astter Y, Treco E, Peyser B, Gussio R, Nguyen T, Eaton B, Postnikova E, Murphy M, Shrestha P, Bulut H, Hattorri SI, Mitsuya H, Yarchoan R. Davis DA, et al. Among authors: postnikova e. RSC Med Chem. 2024 Sep 27;15(12):4193-205. doi: 10.1039/d4md00454j. Online ahead of print. RSC Med Chem. 2024. PMID: 39371432 Free article.
Characterization of therapeutic antibody efficacy against multiple SARS-CoV-2 variants in the hamster model.
Cong Y, Dixit S, Perry DL, Huzella LM, Kollins E, Byrum R, Anthony SM, Drawbaugh D, Lembirik S, Postnikova E, Eaton B, Murphy M, Kocher G, Hadley K, Marketon AE, Bernbaum RM, Hischak AMW, Hart R, Vaughan N, Wada J, Qin J, St Claire MC, Schmaljohn CS, Holbrook MR. Cong Y, et al. Among authors: postnikova e. Antiviral Res. 2024 Oct;230:105987. doi: 10.1016/j.antiviral.2024.105987. Epub 2024 Aug 13. Antiviral Res. 2024. PMID: 39147143 Free article.
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants.
Wirnsberger G, Monteil V, Eaton B, Postnikova E, Murphy M, Braunsfeld B, Crozier I, Kricek F, Niederhöfer J, Schwarzböck A, Breid H, Jimenez AS, Bugajska-Schretter A, Dohnal A, Ruf C, Gugenberger R, Hagelkruys A, Montserrat N, Holbrook MR, Oostenbrink C, Shoemaker RH, Mirazimi A, Penninger JM. Wirnsberger G, et al. Among authors: postnikova e. bioRxiv [Preprint]. 2021 Sep 10:2021.09.10.459744. doi: 10.1101/2021.09.10.459744. bioRxiv. 2021. Update in: EMBO Mol Med. 2022 Aug 8;14(8):e15230. doi: 10.15252/emmm.202115230 PMID: 34545368 Free PMC article. Updated. Preprint.
Repeated mRNA vaccination sequentially boosts SARS-CoV-2-specific CD8+ T cells in persons with previous COVID-19.
Ford ES, Mayer-Blackwell K, Jing L, Laing KJ, Sholukh AM, St Germain R, Bossard EL, Xie H, Pulliam TH, Jani S, Selke S, Burrow CJ, McClurkan CL, Wald A, Greninger AL, Holbrook MR, Eaton B, Eudy E, Murphy M, Postnikova E, Robins HS, Elyanow R, Gittelman RM, Ecsedi M, Wilcox E, Chapuis AG, Fiore-Gartland A, Koelle DM. Ford ES, et al. Among authors: postnikova e. Nat Immunol. 2024 Jan;25(1):166-177. doi: 10.1038/s41590-023-01692-x. Epub 2023 Dec 6. Nat Immunol. 2024. PMID: 38057617 Free PMC article.
Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants.
Monteil V, Eaton B, Postnikova E, Murphy M, Braunsfeld B, Crozier I, Kricek F, Niederhöfer J, Schwarzböck A, Breid H, Devignot S, Klingström J, Thålin C, Kellner MJ, Christ W, Havervall S, Mereiter S, Knapp S, Sanchez Jimenez A, Bugajska-Schretter A, Dohnal A, Ruf C, Gugenberger R, Hagelkruys A, Montserrat N, Kozieradzki I, Hasan Ali O, Stadlmann J, Holbrook MR, Schmaljohn C, Oostenbrink C, Shoemaker RH, Mirazimi A, Wirnsberger G, Penninger JM. Monteil V, et al. Among authors: postnikova e. EMBO Mol Med. 2022 Aug 8;14(8):e15230. doi: 10.15252/emmm.202115230. Epub 2022 Jul 4. EMBO Mol Med. 2022. PMID: 35781796 Free PMC article.
Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters.
Cong Y, Mucker EM, Perry DL, Dixit S, Kollins E, Byrum R, Huzella L, Kim R, Josleyn M, Kwilas S, Stefan C, Shoemaker CJ, Koehler J, Coyne S, Delp K, Liang J, Drawbaugh D, Hischak A, Hart R, Postnikova E, Vaughan N, Asher J, St Claire M, Hanson J, Schmaljohn C, Eakin AE, Hooper JW, Holbrook MR. Cong Y, et al. Among authors: postnikova e. Antiviral Res. 2023 May;213:105589. doi: 10.1016/j.antiviral.2023.105589. Epub 2023 Mar 30. Antiviral Res. 2023. PMID: 37003305 Free PMC article.
Naturally Acquired SARS-CoV-2 Immunity Persists for Up to 11 Months Following Infection.
De Giorgi V, West KA, Henning AN, Chen LN, Holbrook MR, Gross R, Liang J, Postnikova E, Trenbeath J, Pogue S, Scinto T, Alter HJ, Cantilena CC. De Giorgi V, et al. Among authors: postnikova e. J Infect Dis. 2021 Oct 28;224(8):1294-1304. doi: 10.1093/infdis/jiab295. J Infect Dis. 2021. PMID: 34089610 Free PMC article.
Scalable, Micro-Neutralization Assay for Qualitative Assessment of SARS-CoV-2 (COVID-19) Virus-Neutralizing Antibodies in Human Clinical Samples.
Bennett RS, Postnikova EN, Liang J, Gross R, Mazur S, Dixit S, Lukin VV, Kocher G, Yu S, Georgia-Clark S, Gerhardt D, Cai Y, Marron L, Holbrook MR. Bennett RS, et al. bioRxiv [Preprint]. 2021 Mar 5:2021.03.05.434152. doi: 10.1101/2021.03.05.434152. bioRxiv. 2021. Update in: Viruses. 2021 May 12;13(5):893. doi: 10.3390/v13050893 PMID: 33688658 Free PMC article. Updated. Preprint.
81 results